Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Jordan Dermatology and Hair Transplantation Center, Tehran, Iran.
Skin Res Technol. 2024 Sep;30(9):e13907. doi: 10.1111/srt.13907.
The emergence of horizontal neck wrinkles is increasingly becoming a focal point for both cosmetic professionals and clients. Various treatment approaches must be considered to address this issue effectively, owing to its diverse underlying causes. The study explores the potential of utilizing the Endolift laser in conjunction with nanofat injection as a viable treatment option.
Twenty patients with horizontal neck wrinkles involved in the study. Ten patients underwent treatment with a combination of Endolift laser and nanofat injection and 10 patients treated with nanofat injection alone. The participants were monitored for 6 months post-treatment. Biometric measurements were utilized to assess outcomes, including changes in volume, depth, and area of the wrinkles, skin elasticity, as well as the diameter and density of the epidermis and dermis in the treated area. Skin improvement was evaluated by two independent dermatologists, who compared before and after photos in a blinded manner. Patient satisfaction levels were also documented.
The Visioface analysis showed a notable decrease in neck wrinkle depth and area in both groups. However, the group receiving the combination treatment of Endolift laser and nanofat exhibited a significantly greater improvement compared to the group treated with nanofat alone. Skin ultrasonography results demonstrated an increase in thickness and density of the dermis and epidermis in both groups. Particularly, the group treated with Endolift laser-nanofat displayed significant enhancements in dermis and epidermis density and thickness when contrasted with the nanofat-only group. Analysis with Cutometer revealed a marked enhancement in skin elasticity in the Endolift-nanofat treated group in comparison to the nanofat-only treated group. Furthermore, in the Endolift-nanofat treated group, a substantial majority (90%) of patients exhibited improvement. Patient evaluations highlighted significant distinctions between the two groups, with 95% of patients in the Endolift-nanofat treated group demonstrating enhancement.
Both methods notably enhance horizontal neck wrinkles; nevertheless, the combination of endolift laser and nanofat seems to be more efficient for treating horizontal neck wrinkles.
横向颈纹越来越成为美容专业人士和客户关注的焦点。由于其潜在原因的多样性,必须考虑各种治疗方法来有效解决这个问题。本研究探讨了将 Endolift 激光与纳米脂肪注射联合应用作为一种可行的治疗选择的潜力。
本研究共纳入 20 例横向颈纹患者。其中 10 例患者接受了 Endolift 激光联合纳米脂肪注射治疗,10 例患者仅接受了纳米脂肪注射治疗。治疗后对患者进行了 6 个月的监测。采用生物计量学测量评估治疗效果,包括皱纹体积、深度和面积的变化,皮肤弹性,以及治疗区域表皮和真皮的直径和密度。两位独立的皮肤科医生对皮肤改善情况进行了评估,他们以盲法比较了治疗前后的照片。还记录了患者的满意度。
Visioface 分析显示,两组患者的颈纹深度和面积均显著减小。然而,接受 Endolift 激光联合纳米脂肪治疗的组比仅接受纳米脂肪治疗的组改善更为显著。皮肤超声检查结果显示两组真皮和表皮的厚度和密度均增加。特别是与仅接受纳米脂肪治疗的组相比,接受 Endolift 激光-纳米脂肪治疗的组在真皮和表皮密度和厚度方面均有显著提高。Cutometer 分析显示,与仅接受纳米脂肪治疗的组相比,接受 Endolift 激光-纳米脂肪治疗的组的皮肤弹性显著增强。此外,在接受 Endolift 激光-纳米脂肪治疗的组中,绝大多数(90%)患者的病情有改善。患者评估突出了两组之间的显著差异,接受 Endolift 激光-纳米脂肪治疗的组中有 95%的患者病情改善。
两种方法均可显著改善横向颈纹;然而,Endolift 激光与纳米脂肪联合应用似乎对治疗横向颈纹更为有效。