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[冰岛多动症药物治疗的高流行率表明多动症在冰岛被过度诊断]

[High prevalence of treatment with ADHD medicines indicates overdiagnosis of ADHD in Iceland].

作者信息

Ingimarsson Oddur, Gudbrandsdottir Ragna Kristin, Lauth Bertrand Andre Marc, Sigurdsson Engilbert

机构信息

University of Iceland, Faculty of Medicine, Mental Health Services, Landspitali University Hospital of Iceland.

University of Iceland, Faculty of Medicine, Landspitali University Hospital of Iceland.

出版信息

Laeknabladid. 2024 Sep;110(9):402-410. doi: 10.17992/lbl.2024.09.804.

Abstract

INTRODUCTION

ADHD is a neurodevelopmental disorder characterized by hyperactivity, inattention and impulsivity. For many the core symptoms become less troubling in adulthood. Treatment with stimulants is considered the most efficacious treatment for ADHD. Large high-quality studies have estimated the prevalence of AHDH to be 3,4-7,2% for children and adolescents and 2,5-6,8% for young adults. The aim of this study was to estimate the proportion of Icelanders who have received an ADHD diagnosis based on ADHD-medication prescriptions since an ADHD diagnosis is a prerequisite for such prescriptions in Iceland.

METHODS

This population-based retrospective cohort study included all Icelanders 7-70 years old who received a prescription for an ADHD drug from 1.1.2004-31.12.2023. Every citizen receiving a prescription is included in the Icelandic Prescription Medicines Registry (IPMR).

RESULTS

In 2023 14,7% of youth, 7-17 years of age, received a prescription for an ADHD medication, 17,7% of boys and 11,6% of girls. Among 12-17 years old youth the proportion was higher still, 17,6%, 20,1% for boys and 14,6% for girls. For 18-44 years old adults the proportion was 10,2%, 9,4% for males and 11,0% for females. From 2010-2023 the increase in prescriptions for 7-17 years old boys has been 93% but 224% for girls. For 18-44 years old males the increase has been 414% for males and 543% for females during this period. The incidence of new ADHD prescriptions for 7-17 years old boys from 2021-2023 was 10,9 and 13,5 for girls per 1000, respectively. For 18-44 years old the incidence in the years 2021-2023 was 18,7 for males and 19,2 for females per 1000, respectively.

CONCLUSION

The prevalence of Icelanders who have received an ADHD diagnosis is double to treble that observed in the best available studies in other populations. We therefore call for an urgent review of how ADHD diagnoses are made in Iceland because it is obvious that the current system leads to overdiagnosis and inappropriate treatment.

摘要

引言

注意力缺陷多动障碍(ADHD)是一种神经发育障碍,其特征为多动、注意力不集中和冲动。对许多人来说,这些核心症状在成年后会减轻。兴奋剂治疗被认为是治疗ADHD最有效的方法。大型高质量研究估计,儿童和青少年中ADHD的患病率为3.4%-7.2%,年轻人中为2.5%-6.8%。本研究的目的是根据ADHD药物处方来估计冰岛接受过ADHD诊断的人群比例,因为在冰岛,ADHD诊断是开具此类处方的先决条件。

方法

这项基于人群的回顾性队列研究纳入了2004年1月1日至2023年12月31日期间所有7至70岁且接受过ADHD药物处方的冰岛人。每位接受处方的公民都被纳入冰岛处方药登记系统(IPMR)。

结果

2023年,7至17岁的青少年中,14.7%的人接受了ADHD药物处方,男孩为17.7%,女孩为11.6%。在12至17岁的青少年中,这一比例更高,为17.6%,男孩为20.1%,女孩为14.6%。18至44岁的成年人中,这一比例为10.2%,男性为9.4%,女性为11.0%。从2010年到2023年,7至17岁男孩的处方量增长了93%,而女孩增长了224%。在此期间,18至44岁男性的处方量增长了414%,女性增长了543%。2021年至2023年,7至17岁男孩新ADHD处方的发病率为每1000人中有10.9例,女孩为13.5例。18至44岁人群中,2021年至2023年的发病率分别为男性每1000人中有18.7例,女性为19.2例。

结论

冰岛接受过ADHD诊断的人群患病率是其他人群中现有最佳研究观察到的患病率的两倍至三倍。因此,我们呼吁对冰岛ADHD诊断的方式进行紧急审查显,因为很明显,目前的系统导致了过度诊断和不适当的治疗。

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