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[肺炎支原体感染中的血清免疫球蛋白]

[Serum immunoglobulin in Mycoplasma pneumoniae infection].

作者信息

Baĭzhomartov M S, Shuratov I Kh, Semenova V A, Diuskalieva G U, Stetsenko O G

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Feb(2):68-72.

PMID:3922183
Abstract

The dynamics and nature of serum antibodies in experimental and natural M. pneumoniae infection have been studied. The synthesis of specific IgM, IgA and IgG has been found to occur in the course of infection. During repeated M. pneumoniae infection in guinea pigs, as well as in cases of acute and chronic mycoplasmal pneumonia in humans (at the acute period of the disease), the prevalence of the synthesis of specific IgM is observed. At the acute period of the disease a rise in the quantitative levels of IgM and IgG occurs in patients. High titers of specific IgM (1:32 and greater) determined at the acute period of the disease can serve as the diagnostic criterion of the mycoplasmal etiology of pneumonia.

摘要

对实验性和自然感染肺炎支原体时血清抗体的动态变化及性质进行了研究。已发现在感染过程中会合成特异性IgM、IgA和IgG。在豚鼠反复感染肺炎支原体期间,以及在人类急性和慢性支原体肺炎病例中(在疾病急性期),均观察到特异性IgM合成的普遍性。在疾病急性期,患者体内IgM和IgG的定量水平会升高。在疾病急性期测定的高滴度特异性IgM(1:32及以上)可作为肺炎支原体病因的诊断标准。

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Humoral and cellular immunity in children with Mycoplasma pneumoniae infection: a 1-year prospective study.肺炎支原体感染患儿的体液免疫和细胞免疫:一项为期1年的前瞻性研究。
Clin Diagn Lab Immunol. 2005 Oct;12(10):1246-50. doi: 10.1128/CDLI.12.10.1246-1250.2005.