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创伤后应激障碍和认知加工疗法治疗结束后 9 个月的辩证行为疗法的长期效果。

Long-term effects of dialectical behaviour therapy for posttraumatic stress disorder and cognitive processing therapy 9 months after treatment termination.

机构信息

Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.

Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.

出版信息

Eur J Psychotraumatol. 2024;15(1):2393061. doi: 10.1080/20008066.2024.2393061. Epub 2024 Sep 2.

DOI:10.1080/20008066.2024.2393061
PMID:39221987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11370672/
Abstract

The complexity of posttraumatic stress disorder (PTSD) symptoms related to childhood abuse (CA) present challenges for effective psychotherapeutic treatment. Consequently, there is great interest in the long-term effectiveness of psychological treatments for this population. This study aims to investigate the long-term outcomes of Dialectical Behaviour Therapy for PTSD (DBT-PTSD) and Cognitive Processing Therapy (CPT) 9 months after treatment termination. This is a long-term analysis from a randomised-controlled trial of DBT-PTSD versus CPT (registration number DRKS00005578). Initially, 193 individuals with CA-related PTSD were randomly allocated to receive either DBT-PTSD ( = 98) or CPT ( = 95). The primary outcome the Clinician-administered PTSD-Scale for DSM-5 (CAPS-5) was administred at baseline, treatment completion (15 months post-randomization) and at the 9-month follow-up. Secondary outcomes included self-reported PTSD severity (PCL-5), dissociation (DSS), severity of borderline symptoms (BSL-23), and psychosocial functioning (GAF). No significant changes were observed in the primary (CAPS) and all other outcomes from post-intervention to 9-months follow-up in both the DBT-PTSD (CAPS:  = 15.60, = 14.93) and CPT group (CAPS:  = 18.80,  = 17.41). Between-group analyses at 9-months follow-up were significantly in favour of DBT-PTSD compared to CPT with small to medium effect sizes on all outcomes ranging from = 0.35 on the CAPS to = 0.57 on the BSL-23 and GAF. Our results indicate that treatment effects of psychotherapy addressing complex presentations of PTSD persist 9 months after treatment termination. In addition, the superiority of DBT-PTSD as compared to CPT found at treatment termination, was confirmed at 9-months follow-up. German Clinical Trials Register identifier: DRKS00005578..

摘要

创伤后应激障碍(PTSD)症状的复杂性与儿童期虐待(CA)有关,这给有效的心理治疗带来了挑战。因此,人们对针对这一人群的心理治疗的长期效果非常感兴趣。本研究旨在调查创伤后应激障碍的辩证行为疗法(DBT-PTSD)和认知加工疗法(CPT)在治疗结束后 9 个月的长期效果。这是一项针对 DBT-PTSD 与 CPT 的随机对照试验的长期分析(注册号 DRKS00005578)。最初,193 名患有 CA 相关 PTSD 的个体被随机分配接受 DBT-PTSD(n=98)或 CPT(n=95)治疗。主要结局是临床管理 PTSD 量表第五版(CAPS-5),在基线、治疗结束(随机分组后 15 个月)和 9 个月随访时进行评估。次要结局包括自我报告的 PTSD 严重程度(PCL-5)、分离(DSS)、边缘症状严重程度(BSL-23)和心理社会功能(GAF)。在 DBT-PTSD 组(CAPS:=15.60,=14.93)和 CPT 组(CAPS:=18.80,=17.41)中,从干预后到 9 个月随访时,主要结局(CAPS)和所有其他结局均无显著变化。在 9 个月随访时,与 CPT 相比,DBT-PTSD 在所有结局上均具有显著优势,从 CAPS 的效应大小为 0.35 到 BSL-23 和 GAF 的 0.57。我们的研究结果表明,针对 PTSD 复杂表现的心理治疗的治疗效果在治疗结束后 9 个月仍然存在。此外,在治疗结束时发现的 DBT-PTSD 优于 CPT 的优势在 9 个月随访时得到了确认。德国临床试验注册中心标识符:DRKS00005578。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/189d2f98a22b/ZEPT_A_2393061_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/1cb3b2d3e062/ZEPT_A_2393061_F0001_OB.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/54096ffdb144/ZEPT_A_2393061_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/189d2f98a22b/ZEPT_A_2393061_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/1cb3b2d3e062/ZEPT_A_2393061_F0001_OB.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/54096ffdb144/ZEPT_A_2393061_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b81/11370672/189d2f98a22b/ZEPT_A_2393061_F0003_OC.jpg

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