Wager G P, Hanley L S, Farb H F, Knox G E
Am J Obstet Gynecol. 1985 May 1;152(1):51-6. doi: 10.1016/s0002-9378(85)80176-9.
Gas-liquid chromatography has been proposed as a possible tool in the rapid diagnosis of amniotic fluid infections. The analysis is based on the identification of specific organic acids derived from bacterial metabolism when organisms are present within the amniotic fluid. We retrospectively subjected 69 samples of amniotic fluid which had been obtained by transabdominal amniocentesis to analysis by gas-liquid chromatography. Forty-seven samples were derived from patients who either were in premature labor or had premature rupture of membranes with associated premature labor. Twenty-two specimens which served as a comparison group were obtained from patients who underwent amniocentesis for assessment of fetal maturity. The results obtained from chromatographic analysis are presented, and the possible applications of this technique to the clinical situation are discussed.
气液色谱法已被提议作为快速诊断羊水感染的一种可能工具。该分析基于对羊水内存在微生物时细菌代谢产生的特定有机酸的鉴定。我们回顾性地对经腹羊膜穿刺术获取的69份羊水样本进行了气液色谱分析。47份样本来自早产或胎膜早破合并早产的患者。作为对照组的22份样本来自接受羊膜穿刺术以评估胎儿成熟度的患者。文中呈现了色谱分析的结果，并讨论了该技术在临床中的可能应用。
