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[5% 利多卡因透皮贴剂在膝关节镜检查术后镇痛中的疗效]

[Efficacy of transdermal lidocaine 5% patches in postoperative analgesia following knee arthroscopy].

作者信息

Godoy-Salinas E A, De la Rosa-Massieu D, Rodríguez-Piñón E F, Figueroa-García J

机构信息

Servicio de Ortopedia, Hospital Ángeles Mocel. Facultad Mexicana de Medicina de la Universidad La Salle. México.

Unidad de Medicina Familiar No. 26 del Instituto Mexicano del Seguro Social (IMSS). Ciudad de México.

出版信息

Acta Ortop Mex. 2024 Jul-Aug;38(4):220-225.

PMID:39222945
Abstract

INTRODUCTION

knee arthroscopy is a common orthopedic procedure associated with postoperative pain, so optimizing pain management is essential for patient recovery and satisfaction. Lidocaine, a local anesthetic with well-established safety profiles, offers a potential alternative to traditional analgesic methods. Research regarding lidocaine patches has been conducted in several types of surgeries (laparoscopy, gynecological surgery, prostatectomy, etc.) showing promising results for some. This study investigates the effectiveness of transdermal lidocaine 5% patches as a novel approach to postoperative analgesia after knee arthroscopy.

MATERIAL AND METHODS

a randomized, single-blind, placebo-controlled trial was conducted with participants undergoing knee arthroscopy. Patients were divided into two groups: one receiving transdermal lidocaine 5% patches and the other a placebo, both along traditional postoperative pain management, and using opioid only in cases with moderate-severe pain. Pain scores, opioid consumption, and patient-reported outcomes were assessed at various postoperative intervals.

RESULTS

there was a significant reduction in pain scores and opioid consumption in the lidocaine patch group compared to the placebo group.

CONCLUSIONS

transdermal lidocaine 5% patches emerge as a promising adjunct to postoperative pain management in knee arthroscopy patients. Their ease of application, minimal side effects, and opioid-sparing effects contribute to a multifaceted analgesic approach. This study underscores the potential of transdermal lidocaine patches in enhancing the overall postoperative experience for knee arthroscopy patients, advocating for their consideration in clinical practice.

摘要

引言

膝关节镜检查是一种常见的骨科手术,术后会伴有疼痛,因此优化疼痛管理对患者的恢复和满意度至关重要。利多卡因是一种安全性已得到充分证实的局部麻醉剂,为传统镇痛方法提供了一种潜在的替代方案。关于利多卡因贴片的研究已在多种类型的手术(腹腔镜手术、妇科手术、前列腺切除术等)中进行,对一些手术显示出了有前景的结果。本研究调查了5%的透皮利多卡因贴片作为膝关节镜检查术后镇痛新方法的有效性。

材料与方法

对接受膝关节镜检查的参与者进行了一项随机、单盲、安慰剂对照试验。患者被分为两组:一组接受5%的透皮利多卡因贴片,另一组接受安慰剂,两组均采用传统的术后疼痛管理方法,仅在中重度疼痛的情况下使用阿片类药物。在术后不同时间间隔评估疼痛评分、阿片类药物消耗量和患者报告的结果。

结果

与安慰剂组相比,利多卡因贴片组的疼痛评分和阿片类药物消耗量显著降低。

结论

5%的透皮利多卡因贴片成为膝关节镜检查患者术后疼痛管理的一种有前景的辅助方法。其易于应用、副作用最小以及节省阿片类药物的作用有助于形成多方面的镇痛方法。本研究强调了透皮利多卡因贴片在改善膝关节镜检查患者整体术后体验方面的潜力,主张在临床实践中考虑使用它们。

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