Liu X, Shang B, Niu Y Y
Occupational Disease Department Ⅱ, Shandong Zibo Occupational Disease Prevention and Control Hospital, Zibo 255000, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2024 Aug 20;42(8):624-626. doi: 10.3760/cma.j.cn121094-20230206-00031.
This paper analyzes the pathogenesis, clinical characteristics, treatment measures and prognosis of a case of methemoglobin and hemolytic anemia caused by acute nitrogen trifluoride poisoning. The patient with occupational exposure to nitrogen trifluoride was treated immediately after the onset of illness, methemoglobin was monitored and a comprehensive examination was conducted. After comprehensive analysis, it was considered that acute nitrogen trifluoride poisoning could cause methemoglobinemia, hemolytic anemia and liver injury. The patient was disengaged and given symptomatic treatment such as oxygen therapy, methylene blue, low-dose methylpredrone, vitamin C and reduced glutathione. The prognosis of the patient is good, which provides a reference for the clinical treatment and occupational health examination of nitrogen trifluoride poisoning.
本文分析了1例急性三氟化氮中毒致高铁血红蛋白血症和溶血性贫血的发病机制、临床特点、治疗措施及预后。该职业性接触三氟化氮患者发病后立即接受治疗，监测高铁血红蛋白并进行全面检查。综合分析后认为，急性三氟化氮中毒可导致高铁血红蛋白血症、溶血性贫血和肝损伤。患者脱离接触，并给予吸氧、亚甲蓝、小剂量甲泼尼龙、维生素C和还原型谷胱甘肽等对症治疗。患者预后良好，为三氟化氮中毒的临床治疗及职业健康检查提供了参考。
