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It has been reported that a scenario-based cognitive behavioral therapy mobile app including Todac Todac was effective in improving depression in the general public. However, no study has been conducted on whether Todac Todac is effective in dialysis patients. Therefore, this study was intended to determine whether the use of this app was effective in improving depression in dialysis patients. Sixty-five end-stage kidney disease patients receiving dialysis at Soonchunhyang University Cheonan Hospital were randomly assigned to the Todac Todac app program (experimental group) or an E-moods daily mood chart app program (control group) for 3 weeks. The degree of depression was measured before and after using the app.After the end of the 3-week program, a small but significant improvement was observed in the Trait anxiety (p < 0.05) and Beck depression index (p < 0.05) in E-moods group and DAS-K scores (p < 0.05) in Todac Todac group. However, no differences were seen in any parameters between the two groups. In addition, Todac Todac was not statistically more effective than the control intervention in the subgroup analysis. The Todac Todac, a scenario-based cognitive behavioral therapy mobile app, seemed to have a limited effect on improving depression in dialysis patients. Therefore, it is necessary to develop new tools to improve depression in dialysis patients.

据报道，一种基于情景的认知行为疗法移动应用程序（包括 Todac Todac）可有效改善普通人群的抑郁症状。然而，尚未有研究探讨 Todac Todac 是否对透析患者有效。因此，本研究旨在确定使用该应用程序是否能有效改善透析患者的抑郁症状。

将 65 名在顺天乡大学天安医院接受透析治疗的终末期肾病患者随机分配至 Todac Todac 应用程序（实验组）或 E-moods 日常情绪图表应用程序（对照组），进行为期 3 周的治疗。在使用应用程序前后测量抑郁程度。

在 3 周的方案结束后，E-moods 组的特质焦虑（p<0.05）和贝克抑郁指数（p<0.05）以及 Todac Todac 组的 DAS-K 评分（p<0.05）均有较小但显著的改善。然而，两组之间的任何参数均无差异。此外，在亚组分析中，Todac Todac 与对照组干预相比并没有统计学上的更优效果。

基于情景的认知行为疗法移动应用程序 Todac Todac 似乎对改善透析患者的抑郁症状效果有限。因此，有必要开发新的工具来改善透析患者的抑郁症状。