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影响社区居民安全用药的因素:一项横断面研究。

Factors influencing safe use of drugs among community residents: a cross-sectional study.

机构信息

School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.

NMPA Key Laboratory for Technology Research and Evaluation of Pharmacovigilance, Guangzhou, Guangdong, China.

出版信息

BMC Public Health. 2024 Sep 2;24(1):2373. doi: 10.1186/s12889-024-19911-x.

Abstract

BACKGROUND

Researchers have paid little attention to the safety of drug use among community residents (CRs). Irrational use of drugs can lead to health risks. We investigated the situation of knowledge-attitude-practices (KAP) of CRs in Shenzhen (China) for safe use of drugs, and analyzed the main factors influencing drug use.

METHODS

A multi-stage, random sampling method was used. We used a validated questionnaire to conduct an online questionnaire survey on the demographic characteristics and KAP of safe use of drugs of CRs in 10 administrative districts of Shenzhen City. The KAP score of safe use of drugs of CRs was analyzed. Influencing factors were identified using a single-factor chi-squared test and binary logistic regression analysis.

RESULTS

A total of 7269 valid questionnaires were collected. The average scores of knowledge, attitude, and behavior were (9.08 ± 1.49) (possible range: 0-10), (37.82 ± 3.96) (possible range: 8-40), and (35.82 ± 4.56) (possible range: 8-40), respectively, indicating that they had a better grasp of safe use of drugs. Logistic regression analysis showed that sex, age, education level, occupation, monthly household income per capita, marital status, health status, and different sources of information were the main factors affecting the knowledge and behavior of safe use of drugs of CRs. In addition to the marital status variable, other variables also have a significant impact on attitude towards safe use of drugs of CRs.

CONCLUSIONS

Male sex, lower education level, lower income level, average/poor self-rated health status, and single source of drug-use information were the main factors affecting safe use of drugs based on KAP theory. The government and medical workers should carry out various forms of drug-education activities for people with different needs, encourage CRs to learn safe use of drugs, and promote safe use of drugs by CRs through diverse information sources.

摘要

背景

研究人员对社区居民(CRs)用药安全关注甚少。不合理用药会导致健康风险。我们调查了深圳市 CRs 安全用药知识-态度-实践(KAP)状况,并分析了影响用药的主要因素。

方法

采用多阶段、随机抽样方法,采用经过验证的问卷,对深圳市 10 个行政区 CRs 的人口统计学特征和安全用药 KAP 进行在线问卷调查。分析 CRs 安全用药 KAP 得分,采用单因素 χ 2 检验和二项 logistic 回归分析识别影响因素。

结果

共收集有效问卷 7269 份。知识、态度和行为的平均得分分别为(9.08±1.49)(得分范围:0-10)、(37.82±3.96)(得分范围:8-40)和(35.82±4.56)(得分范围:8-40),表明他们对安全用药有较好的掌握。Logistic 回归分析显示,性别、年龄、教育水平、职业、人均月家庭收入、婚姻状况、健康状况和不同信息来源是影响 CRs 安全用药知识和行为的主要因素。除婚姻状况变量外,其他变量对 CRs 安全用药态度也有显著影响。

结论

基于 KAP 理论,男性、教育水平较低、收入水平较低、自评健康状况一般/较差、单一用药信息来源是影响安全用药的主要因素。政府和医务人员应针对不同需求的人群开展各种形式的药物教育活动,鼓励 CRs 学习安全用药知识,通过多样化的信息来源促进 CRs 的安全用药。

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