Xu Kun, Zhang Jiefan, Ma Wei, Wang Yongyu, Chen Bo, Gao Ningyang, Pang Jian, Zhan Hongsheng
Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese Medicine, Shanghai, People's Republic of China.
J Pain Res. 2024 Aug 29;17:2811-2822. doi: 10.2147/JPR.S469176. eCollection 2024.
Shi's Knee Daoyin (SKD) exercise is a treatment derived from Traditional Chinese exercise (TCE) specifically designed for lower limb health care. This study aimed to assess the feasibility of conducting a randomized controlled trial to explore the effectiveness of SKD exercise in treating knee osteoarthritis (KOA).
Participants were randomized to receive Health Education (HE) or SKD exercise. The primary outcomes were feasibility and safety outcomes, including participant recruitment rate, retention rate, as well as adherence to intervention. The secondary outcomes included Visual Analogue Scale (VAS) scores for pain, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, the 20-Meter Walk Test (20-MWT) and the 5-times Chair-Stand Test (5-CST).
The results indicate that out of 89 individuals invited to participate in the study, 72 were eligible and agreed to participate, resulting in a recruitment rate of 80.9%. All participating patients completed the follow-up and were included in the analysis; no patients dropped out of the study due to adverse events. The secondary outcome measures showed that after twelve weeks of treatment, the VAS score, WOMAC total score, WOMAC pain score, WOMAC stiffness score, and WOMAC function score of patients in the HE group and SKD group all improved, but the improvement was more significant in the SKD group. The 20-MWT of SKD group after treatment was significantly shorter than before treatment (<0.001); There was no significant difference in 20-MWT between the HE group and baseline after treatment. The performance of the two groups of patients improved in 5-CST, but there was no statistical difference between the two groups after treatment (=2.439).
This study evaluated the feasibility and effectiveness of home-based SKD exercise intervention in alleviating symptoms in patients with symptomatic KOA, providing valuable information for designing an appropriate randomized controlled study.
施氏膝道引术是一种源自中国传统运动的疗法，专为下肢保健而设计。本研究旨在评估开展一项随机对照试验以探究施氏膝道引术治疗膝关节骨关节炎（KOA）有效性的可行性。
参与者被随机分为接受健康教育（HE）组或施氏膝道引术锻炼组。主要结局为可行性和安全性结局，包括参与者招募率、留存率以及对干预措施的依从性。次要结局包括疼痛视觉模拟量表（VAS）评分、西安大略和麦克马斯特大学骨关节炎指数（WOMAC）评分、20米步行试验（20-MWT）以及5次起坐试验（5-CST）。
结果表明，在受邀参与研究的89人中，72人符合条件并同意参与，招募率为80.9%。所有参与患者均完成随访并纳入分析；无患者因不良事件退出研究。次要结局指标显示，治疗12周后，HE组和施氏膝道引术组患者的VAS评分、WOMAC总分、WOMAC疼痛评分、WOMAC僵硬评分及WOMAC功能评分均有所改善，但施氏膝道引术组改善更为显著。施氏膝道引术组治疗后的20-MWT显著短于治疗前（<0.001）；治疗后HE组与基线的20-MWT无显著差异。两组患者在5-CST中的表现均有改善，但治疗后两组间无统计学差异（=2.4３9）。
本研究评估了居家施氏膝道引术锻炼干预缓解症状性KOA患者症状的可行性和有效性，为设计合适的随机对照研究提供了有价值的信息。
