Fehér Zsuzsanna, Richter Dóra, Dargó Gyula, Kupai József
Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary.
Beilstein J Org Chem. 2024 Aug 26;20:2129-2142. doi: 10.3762/bjoc.20.183. eCollection 2024.
Organocatalysis has become a powerful tool in synthetic chemistry, providing a cost-effective alternative to traditional catalytic methods. The immobilisation of organocatalysts offers the potential to increase catalyst reusability and efficiency in organic reactions. This article reviews the key parameters that influence the effectiveness of immobilised organocatalysts, including the type of support, immobilisation techniques and the resulting interactions. In addition, the influence of these factors on catalytic activity, selectivity and recyclability is discussed, providing an insight into optimising the performance of immobilised organocatalysts for practical applications in organic chemistry.
有机催化已成为合成化学中的一种强大工具,为传统催化方法提供了一种经济高效的替代方案。有机催化剂的固定化提供了提高有机反应中催化剂可重复使用性和效率的潜力。本文综述了影响固定化有机催化剂有效性的关键参数,包括载体类型、固定化技术以及由此产生的相互作用。此外,还讨论了这些因素对催化活性、选择性和可回收性的影响,为优化固定化有机催化剂在有机化学实际应用中的性能提供了见解。