McNicholas Daniel Peter, Taylor Alexander, Baird Andrew D
Aintree University Hospital, Liverpool University Hospital Foundation Trust, Lower Lane, Fazakerley, Liverpool, England, L9 7AL.
Ir J Med Sci. 2024 Dec;193(6):3059-3064. doi: 10.1007/s11845-024-03798-z. Epub 2024 Sep 3.
Male urethral stricture affects 100 in 100,000 men. These are investigated using uroflowmetry, retrograde urethrography and cystourethroscopy. Management is usually endoscopic with urethral dilation or direct visual internal urethrotomy, although they have high failure rates. It is now recommended that urethroplasty is performed earlier. In this study we have reviewed a single surgeons experience with urethroplasty and patient outcomes.
We retrospectively reviewed a prospectively maintained database of all urethroplasty operations performed in our hospital over a 5 -year period.
Forty-five patients were identified, with a mean age of 46. The most common presenting symptom was poor flow (100%). Uroflowmetry was performed in 31 of 45 patients(69%). More patients had a urethrogram (58%) than flexible cystoscopy (38%). Most strictures were idiopathic (67%). Mean stricture length was 2.6 cm. 71% did not require any further intervention. Five patients required repeat surgery. Four required DVIU and one required a repeat urethroplasty.
The most popular techniques for urethroplasty in the UK are augmentation urethroplasty using a buccal mucosal graft and anastomotic urethroplasty, both of which we describe. There are variations in what is deemed as successful surgery. The most widely used definition is 'the lack of need for any further operative intervention'. We have recently adopted Patient Reported Outcome Measures using a validated questionnaire to measure the patients perception of a successful outcome. Complex strictures have a higher incidence of complications. 42% of our cohort were complex and we describe results comparable to the published literature.
男性尿道狭窄在每10万名男性中的发病率为100例。通常采用尿流率测定、逆行尿道造影和膀胱尿道镜检查来对其进行评估。尽管尿道扩张术和直视下内切开术的失败率很高,但这些疾病的治疗通常采用内镜治疗。现在建议应尽早进行尿道成形术。在本研究中,我们回顾了一位外科医生进行尿道成形术的经验及患者的治疗结果。
我们回顾性分析了我院在5年期间前瞻性维护的所有尿道成形术手术数据库。
共确定了45例患者,平均年龄为46岁。最常见的症状是尿流不畅(100%)。45例患者中有31例(69%)进行了尿流率测定。进行尿道造影的患者(58%)比进行软性膀胱镜检查的患者(38%)更多。大多数狭窄为特发性(67%)。平均狭窄长度为2.6厘米。71%的患者无需任何进一步干预。5例患者需要再次手术。4例需要进行直视下内切开术,1例需要再次进行尿道成形术。
在英国,最常用的尿道成形术技术是使用颊黏膜移植的扩大尿道成形术和吻合性尿道成形术,我们对这两种技术都进行了描述。对于什么是成功的手术存在差异。最广泛使用的定义是“无需任何进一步的手术干预”。我们最近采用了患者报告结局测量方法,使用经过验证的问卷来衡量患者对成功结局的看法。复杂狭窄的并发症发生率更高。我们队列中的42%为复杂狭窄,我们描述的结果与已发表的文献相当。