School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Department of Neurosurgery, New York University Grossman School of Medicine, New York City, NYC, USA.
Neurosurg Rev. 2024 Sep 3;47(1):527. doi: 10.1007/s10143-024-02814-1.
Deep brain stimulation (DBS) is a neurosurgical procedure that utilizes implanted electrodes and electrical stimulation for the treatment of neurological disorders. In cases where patients present with severe functional impairment while being refractory to less invasive treatment options, DBS is considered "gold standard." Still, DBS-related work is still widely under investigation, with ethical issues arising that may impact a patient's physical and psycho-social status. These include patient selection, informed consent, patient autonomy, pre-operation counseling and professional psycho-social preparation and follow-up support. Bioethicists and philosophers have increasingly worked together with in clinicians and researchers to identify, address and present ethical consideration in both clinical practice and research to balance the risk-benefit ratio in DBS treatment for obsessive-compulsive disorder.
脑深部电刺激(DBS)是一种神经外科手术,利用植入的电极和电刺激来治疗神经疾病。在患者对非侵入性治疗选择有抗药性而出现严重功能障碍的情况下,DBS 被认为是“金标准”。尽管如此,DBS 相关的工作仍在广泛研究中,出现了可能影响患者身体和心理社会状况的伦理问题。这些问题包括患者选择、知情同意、患者自主性、术前咨询以及专业的心理社会准备和随访支持。生物伦理学家和哲学家越来越多地与临床医生和研究人员合作,以在临床实践和研究中确定、解决和提出伦理考虑因素,以平衡 DBS 治疗强迫症的风险效益比。