Divisão de Urologia, Hospital Brigadeiro, São Paulo, SP, Brasil.
Divisão de Urologia, Hospital Militar de Área de São Paulo, São Paulo, SP, Brasil.
Int Braz J Urol. 2024 Nov-Dec;50(6):746-753. doi: 10.1590/S1677-5538.IBJU.2024.0341.
To assess the impact of thinness on the outcome of the percutaneous nephrolithotomy (PCNL).
A matched case-control study was performed using a prospectively collected database of all patients who underwent PCNL between June 2011 and October 2021. The patients were stratified into two groups according to their phenotypic characteristics, arbitrarily defined according to their body mass index (BMI): <0kg/m2 (Group 1, very thin patients, G<20) and ≥25 kg/m2 (Group 2, non-thin patients, G≥25). Patients were randomly matched based on Guy's Stone Score (GSS) according to case complexity at a ratio of 1:3.
A total of 204 patients were enrolled in this study: 51 patients (G<20) and 153 controls (G≥25). Complications occurred in 15.2% of the patients, with 5.4% of these complications classified as major complications (Clavien grade ≥ 3). According to complications there were no significant differences between the groups. The overall complication rates were 17.6% in the G<20 and 14.4% in the G≥25 (p = 0.653). The major complication rates were 3.9% in the G<20 and 5.8% in the G≥25 (p=0.429). No differences in transfusion or urinary fistula rates were found.
In this study, very thin patients were not at a higher risk of complications when submitted to PCNL than in those with a BMI of ≥25 kg/m2. Apparently, this technique can be used in these patients, just as it is used in any other type of patient, independently of their BMI.
评估消瘦对经皮肾镜碎石术(PCNL)结局的影响。
本研究采用回顾性数据库,对 2011 年 6 月至 2021 年 10 月期间接受 PCNL 的所有患者进行了一项匹配病例对照研究。根据患者的体质量指数(BMI),将患者分为两组:<0kg/m2(第 1 组,极瘦患者,G<20)和≥25kg/m2(第 2 组,非瘦患者,G≥25)。根据结石复杂性,按照 1:3 的比例,根据 Guy 结石评分(GSS)对患者进行随机匹配。
本研究共纳入 204 例患者:51 例(G<20)和 153 例对照(G≥25)。15.2%的患者发生并发症,其中 5.4%的并发症为严重并发症(Clavien 分级≥3)。两组之间在并发症方面无显著差异。G<20 组总的并发症发生率为 17.6%,G≥25 组为 14.4%(p=0.653)。G<20 组严重并发症发生率为 3.9%,G≥25 组为 5.8%(p=0.429)。两组在输血或尿瘘发生率方面无差异。
在这项研究中,与 BMI≥25kg/m2 的患者相比,极瘦患者接受 PCNL 时发生并发症的风险并未增加。显然,该技术可用于这些患者,就像用于任何其他类型的患者一样,与 BMI 无关。