Indiana University Department of Surgery, Indianapolis, Indiana.
Division of Trauma and Acute Care Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
J Surg Res. 2024 Oct;302:790-797. doi: 10.1016/j.jss.2024.07.072. Epub 2024 Sep 2.
Geriatric trauma patients experience disproportionate adverse outcomes compared to younger patients with similar injuries and represent an important target for quality improvement. Our institution created a Geriatric Trauma Intensive Care Unit (ICU) Admission Guideline to identify high-risk patients and elevate their initial level of care. The goal of implementation was reducing unplanned ICU admissions (UIAs), a recognized surrogate marker for adverse outcomes.
The Geriatric Trauma ICU Admission Guideline was implemented on July 1, 2020, at a large academic level-1 trauma center. Using trauma registry data, we retrospectively analyzed geriatric patients who met the criteria for ICU admission 2 y preimplementation and postimplementation. The main outcome was UIAs in the target geriatric population. Secondary outcomes included hospital length of stay, ICU length of stay, ventilator days, mortality, and 30-d readmissions. Characteristics between groups were compared with t-test, Mann-Whitney U test, or chi-square test. Risk-adjusted logistic and negative binomial regressions were used for the categorical and continuous outcomes, respectively.
A total of 1075 patients were identified with 476 in the preimplementation and 599 in the postimplementation group. The groups were similar across most demographic and physiologic characteristics, with the exception of a higher incidence of hypertension in the preimplementation group (77.7% versus 71.6%, P = 0.02) and COVID in the postimplementation group (3.8% versus 0.4%, P < 0.001). While mechanism of injury was similar, there was a higher incidence of traumatic brain injury in the preimplementation group (35.1% versus 26.2%, P = 0.002). In the postimplementation group, there was a higher incidence ≥3 rib fractures (68% versus 61.3%, P = 0.02) and an expected increase in initial ICU level of care (69.5% versus 37.1%, P < 0.001). The odds of a UIA after guideline implementation were reduced by half (adjusted odds ratio 0.52, 95% confidence interval 0.3-0.92). There was not a significant difference in the secondary outcomes of mortality, 30-d readmission, hospital-free days, ICU-free days, or ventilator-free days.
Implementation of the Geriatric Trauma ICU Admission Guideline was associated with a reduction in UIAs by half in the target population. There was not a significant change in hospital-free days, ICU-free days, ventilator-free days, mortality, 30-d readmission, or venous thromboembolism. Further research is needed to better refine admission guidelines, examine the association of preventative admission on delirium, and determination of criteria that would allow safe, earlier downgrade.
与具有相似损伤的年轻患者相比,老年创伤患者的不良预后比例不成比例,这是质量改进的重要目标。我们机构制定了老年创伤重症监护病房(ICU)入院指南,以识别高危患者并提高其初始护理水平。实施的目标是减少非计划 ICU 入院(UIAs),这是不良结果的公认替代标志物。
老年创伤 ICU 入院指南于 2020 年 7 月 1 日在一家大型学术一级创伤中心实施。使用创伤登记数据,我们回顾性分析了在实施前 2 年符合 ICU 入院标准的老年患者。主要结局是目标老年人群中的 UIAs。次要结局包括住院时间、ICU 住院时间、呼吸机天数、死亡率和 30 天再入院率。使用 t 检验、Mann-Whitney U 检验或卡方检验比较组间特征。使用风险调整后的逻辑回归和负二项回归分别对分类和连续结局进行分析。
共确定了 1075 名患者,其中 476 名患者在实施前,599 名患者在实施后。除了实施前组高血压发生率较高(77.7%对 71.6%,P=0.02)和实施后组 COVID 发生率较高(3.8%对 0.4%,P<0.001)外,两组在大多数人口统计学和生理学特征方面相似。虽然损伤机制相似,但实施前组创伤性脑损伤发生率较高(35.1%对 26.2%,P=0.002)。在实施后组,≥3 根肋骨骨折的发生率较高(68%对 61.3%,P=0.02),初始 ICU 护理水平预计也会升高(69.5%对 37.1%,P<0.001)。实施指南后,UIA 的发生几率降低了一半(调整后的优势比 0.52,95%置信区间 0.3-0.92)。死亡率、30 天再入院率、无住院天数、无 ICU 天数或无呼吸机天数等次要结局无显著差异。
老年创伤 ICU 入院指南的实施与目标人群中 UIA 发生率降低了一半有关。无住院天数、无 ICU 天数、无呼吸机天数、死亡率、30 天再入院率或静脉血栓栓塞症无显著变化。需要进一步研究以更好地完善入院指南,检查预防性入院对谵妄的影响,以及确定允许安全、更早降级的标准。