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冷加压试验远程实施的可行性与可接受性

Feasibility and acceptability of remote administration of the cold pressor test.

作者信息

Salwen-Deremer Jessica K, Horrigan Jamie M, Westvold Sarah J, Haythornthwaite Jennifer A

机构信息

Departments of Psychiatry & Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, United States.

Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States.

出版信息

Front Pain Res (Lausanne). 2024 Aug 20;5:1421709. doi: 10.3389/fpain.2024.1421709. eCollection 2024.

Abstract

OBJECTIVE

Quantitative sensory testing is often used to investigate pain in the context of experimental and clinical research studies. However, many of the devices used for QST protocols are only available in resource rich environments, thereby inadvertently limiting the possible pool of participants. Development of remote protocols for appropriate QST measures has the potential to reduce barriers to participation in research.

METHODS

Participants with insomnia and Crohn's disease were recruited as part of a clinical trial. We adapted a remote version of the cold pressor test for use during telehealth-based study assessments. Herein, we present data from the baseline assessments including an assessment of feasibility and acceptability of the task.

RESULTS

100% of participants ( = 28) were able to complete the remote cold pressor test using a combination of materials from their homes and mailed by the study team. Temperature changes during the test were minimal and fairly evenly balanced between increases and decreases. Correlations between submersion time and both general and disease specific pain trended toward significance.

CONCLUSIONS

We demonstrated that a remote version of the cold pressor test is feasible and acceptable in a clinical population and provided a step-by-step protocol for administration to facilitate use in other studies.

摘要

目的

定量感觉测试常用于实验和临床研究中对疼痛的调查。然而,许多用于定量感觉测试方案的设备仅在资源丰富的环境中可用,从而无意中限制了可能的参与者群体。开发适用于定量感觉测试措施的远程方案有可能减少参与研究的障碍。

方法

招募患有失眠症和克罗恩病的参与者作为一项临床试验的一部分。我们改编了冷加压试验的远程版本,用于基于远程医疗的研究评估。在此,我们展示了基线评估的数据,包括对该任务的可行性和可接受性的评估。

结果

100%的参与者(n = 28)能够使用家中的材料和研究团队邮寄的材料完成远程冷加压试验。测试期间的温度变化很小,升温和降温之间相当均匀地平衡。浸泡时间与一般疼痛和疾病特异性疼痛之间的相关性有显著趋势。

结论

我们证明了冷加压试验的远程版本在临床人群中是可行且可接受的,并提供了一个逐步的实施方案,以方便在其他研究中使用。

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