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基人群社区中的暴露前预防:对卢旺达基加利男男性行为者和女性性工作者关于暴露前预防观点的定性研究

PrEP in the key population community: a qualitative study of perspectives on pre-exposure prophylaxis by men who have sex with men and female sex workers in Kigali, Rwanda.

作者信息

Ross Jonathan, Gasana Josephine, Zotova Natalia, Ndabakuranye Giovanni, Mabano Fabiola, Ingabire Charles, Adedimeji Adebola, Murenzi Gad, Patel Viraj V

机构信息

Department of Medicine, Albert Einstein College of Medicine, Bronx NY USA.

Einstein-Rwanda Research and Capacity Building Program, Research for Development (RD Rwanda) and Rwanda Military and Referral Teaching Hospital, Kigali, Rwanda.

出版信息

medRxiv. 2024 Aug 20:2024.08.20.24311545. doi: 10.1101/2024.08.20.24311545.

Abstract

BACKGROUND

Men who have sex with men (MSM) and female sex workers (FSW) are increasingly and disproportionately impacted by HIV in sub-Saharan Africa, yet current PrEP care models in this region are not optimized for these communities. Limited data exist describing experiences and preferences of MSM and FSW with respect to accessing and using PrEP.

METHODS

We conducted qualitative, semi-structured interviews with MSM and FSW recruited from three health centers and seven community organizations in Kigali, Rwanda. Data were analyzed using a mixed deductive and inductive approach to describe key themes related to initiating and adhering to PrEP.

RESULTS

Participants included 18 MSM and 14 FSW; 12 were using PrEP at the time of interview, 9 had previously used PrEP, and 11 had never used it. Participants highlighted the central role of their social networks as key sources of information about and support for PrEP use, and described a strong motivation to use PrEP as a way to protect both themselves and their communities from HIV. While stigma and discrimination were pervasive, these were experienced differently by MSM and FSW. Participants suggested community access points that allowed more discreet and less frequent contact with health care workers as important and desired strategies to improve engagement.

CONCLUSIONS

These findings suggest that leveraging community resources for disseminating information about HIV prevention and delivering PrEP could contribute to successful implementation of PrEP for MSM and FSW in Rwanda and other settings in SSA.

摘要

背景

在撒哈拉以南非洲地区,男男性行为者(MSM)和女性性工作者(FSW)受艾滋病毒影响的程度日益加深且比例过高,但该地区目前的暴露前预防(PrEP)护理模式并未针对这些群体进行优化。关于MSM和FSW在获取和使用PrEP方面的经历及偏好的数据有限。

方法

我们对从卢旺达基加利的三个卫生中心和七个社区组织招募的MSM和FSW进行了定性的半结构化访谈。采用演绎与归纳相结合的方法对数据进行分析,以描述与开始及坚持使用PrEP相关的关键主题。

结果

参与者包括18名MSM和14名FSW;12人在访谈时正在使用PrEP,9人曾使用过PrEP,11人从未使用过。参与者强调其社交网络作为PrEP使用信息及支持的关键来源所发挥的核心作用,并表示使用PrEP的强烈动机是保护自己和社区免受艾滋病毒感染。虽然耻辱感和歧视普遍存在,但MSM和FSW的感受有所不同。参与者认为社区接入点允许与医护人员进行更谨慎且不那么频繁的接触,是提高参与度的重要且理想的策略。

结论

这些研究结果表明,利用社区资源传播艾滋病毒预防信息并提供PrEP,可能有助于在卢旺达及撒哈拉以南非洲其他地区成功为MSM和FSW实施PrEP。

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