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Collective antiretroviral protection: new dimensions of community HIV prevention practices at the intersection of U=U and PrEP.集体抗逆转录病毒保护:U=U 和 PrEP 交叉点上社区艾滋病毒预防实践的新维度。
Lancet HIV. 2024 May;11(5):e341-e344. doi: 10.1016/S2352-3018(24)00034-1. Epub 2024 Mar 18.
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Strategies to Close the PrEP Uptake Gap Among Transgender People and Men Who Have Sex with Men in Tshwane, South Africa: Perspectives from the Community.南非茨瓦内地区跨性别者和男男性行为者中扩大 PrEP (暴露前预防)使用的策略:社区视角。
AIDS Behav. 2024 Jun;28(6):1999-2014. doi: 10.1007/s10461-024-04300-7. Epub 2024 Mar 1.
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A community-based dynamic choice model for HIV prevention improves PrEP and PEP coverage in rural Uganda and Kenya: a cluster randomized trial.基于社区的动态选择模型在乌干达和肯尼亚农村地区提高了 PrEP 和 PEP 的覆盖率:一项集群随机试验。
J Int AIDS Soc. 2023 Dec;26(12):e26195. doi: 10.1002/jia2.26195.
5
Factors associated with retention on pre-exposure prophylaxis among female sex workers in Kigali, Rwanda.卢旺达基加利女性性工作者中与暴露前预防药物留存相关的因素。
PLOS Glob Public Health. 2023 Nov 6;3(11):e0002524. doi: 10.1371/journal.pgph.0002524. eCollection 2023.
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Uptake of Oral HIV Pre-Exposure Prophylaxis (PrEP) and Associated Factors among Female Sex Workers in Tanga, Tanzania.坦桑尼亚坦噶地区女性性工作者口服 HIV 暴露前预防(PrEP)的应用情况及相关因素。
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The Perceived Added Value of Bimonthly Injectable Pre-Exposure Prophylaxis According to West African Men Who Have Sex with Men: A Focus Group Study.西非男男性行为者对双月注射型暴露前预防的感知附加价值:一项焦点小组研究。
AIDS Patient Care STDS. 2023 Oct;37(10):480-488. doi: 10.1089/apc.2023.0097.
8
Uptake and Persistence on HIV Pre-Exposure Prophylaxis Among Female Sex Workers and Men Having Sex with Men in Kigali, Rwanda: A Retrospective Cross-Sectional Study Design.卢旺达基加利女性性工作者和男男性行为者中艾滋病病毒暴露前预防用药的使用情况及持续性:一项回顾性横断面研究设计
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基人群社区中的暴露前预防:对卢旺达基加利男男性行为者和女性性工作者关于暴露前预防观点的定性研究

PrEP in the key population community: a qualitative study of perspectives on pre-exposure prophylaxis by men who have sex with men and female sex workers in Kigali, Rwanda.

作者信息

Ross Jonathan, Gasana Josephine, Zotova Natalia, Ndabakuranye Giovanni, Mabano Fabiola, Ingabire Charles, Adedimeji Adebola, Murenzi Gad, Patel Viraj V

机构信息

Department of Medicine, Albert Einstein College of Medicine, Bronx NY USA.

Einstein-Rwanda Research and Capacity Building Program, Research for Development (RD Rwanda) and Rwanda Military and Referral Teaching Hospital, Kigali, Rwanda.

出版信息

medRxiv. 2024 Aug 20:2024.08.20.24311545. doi: 10.1101/2024.08.20.24311545.

DOI:10.1101/2024.08.20.24311545
PMID:39228702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11370517/
Abstract

BACKGROUND

Men who have sex with men (MSM) and female sex workers (FSW) are increasingly and disproportionately impacted by HIV in sub-Saharan Africa, yet current PrEP care models in this region are not optimized for these communities. Limited data exist describing experiences and preferences of MSM and FSW with respect to accessing and using PrEP.

METHODS

We conducted qualitative, semi-structured interviews with MSM and FSW recruited from three health centers and seven community organizations in Kigali, Rwanda. Data were analyzed using a mixed deductive and inductive approach to describe key themes related to initiating and adhering to PrEP.

RESULTS

Participants included 18 MSM and 14 FSW; 12 were using PrEP at the time of interview, 9 had previously used PrEP, and 11 had never used it. Participants highlighted the central role of their social networks as key sources of information about and support for PrEP use, and described a strong motivation to use PrEP as a way to protect both themselves and their communities from HIV. While stigma and discrimination were pervasive, these were experienced differently by MSM and FSW. Participants suggested community access points that allowed more discreet and less frequent contact with health care workers as important and desired strategies to improve engagement.

CONCLUSIONS

These findings suggest that leveraging community resources for disseminating information about HIV prevention and delivering PrEP could contribute to successful implementation of PrEP for MSM and FSW in Rwanda and other settings in SSA.

摘要

背景

在撒哈拉以南非洲地区,男男性行为者(MSM)和女性性工作者(FSW)受艾滋病毒影响的程度日益加深且比例过高,但该地区目前的暴露前预防(PrEP)护理模式并未针对这些群体进行优化。关于MSM和FSW在获取和使用PrEP方面的经历及偏好的数据有限。

方法

我们对从卢旺达基加利的三个卫生中心和七个社区组织招募的MSM和FSW进行了定性的半结构化访谈。采用演绎与归纳相结合的方法对数据进行分析,以描述与开始及坚持使用PrEP相关的关键主题。

结果

参与者包括18名MSM和14名FSW;12人在访谈时正在使用PrEP,9人曾使用过PrEP,11人从未使用过。参与者强调其社交网络作为PrEP使用信息及支持的关键来源所发挥的核心作用,并表示使用PrEP的强烈动机是保护自己和社区免受艾滋病毒感染。虽然耻辱感和歧视普遍存在,但MSM和FSW的感受有所不同。参与者认为社区接入点允许与医护人员进行更谨慎且不那么频繁的接触,是提高参与度的重要且理想的策略。

结论

这些研究结果表明,利用社区资源传播艾滋病毒预防信息并提供PrEP,可能有助于在卢旺达及撒哈拉以南非洲其他地区成功为MSM和FSW实施PrEP。