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下鼻甲扩展瓣内镜重建复发性垂体瘤鞍底

Endoscopic Reconstruction of the Sellar Floor by Extended Inferior Turbinate Flap in Recurrent Pituitary Tumors.

作者信息

Elsamouly Hatem M, Zaghloul Ahmed, Younis Ahmed, Hadeya Abdelgawad, Ayad Ahmed Adel, Hendawy Mansor Ali, Alaghory Islam M, Barania Mohamed, Ellabbad Mohamed, Attia Mohamed

机构信息

Department of Neurosurgery, Al-Azhar University Damietta Faculty of Medicine, New Damietta, Damietta, Egypt.

Department of Otorhinolaryngology, Al-Azhar University Damietta Faculty of Medicine, New Damietta, Damietta, Egypt.

出版信息

J Neurol Surg B Skull Base. 2023 Aug 29;85(5):509-516. doi: 10.1055/a-2114-4792. eCollection 2024 Oct.

Abstract

This aim of this study was to address the outcome of endoscopic reconstruction of the sellar floor by extended inferior turbinate flap.  This is a retrospective study of 34 patients with a recurrent pituitary tumor. They were treated between March 2018 and December 2021 by endoscopic extended endonasal approach with the reconstruction of the sellar floor by an extended posterior pedicle inferior turbinate flap. The clinical and radiological follow-up was performed immediately postoperation and regularly every 3 months up to 1 year, and the available data from the last follow-up visit were included in the analysis.  The patients' age ranged between 40 and 65 years, with a slight female predominance (55.9%). Headache was the main presentation (47.1%), and functional tumors were found in 50.0% patients. Visual disturbances were field defects among 61.8% and papilledema among 52.9% patients. Preoperative endoscopy revealed postseptectomy as the significant finding (73.5%), followed by postseptectomy and adhesion (14.7%) and finally postseptectomy and hypertrophied inferior turbinate (11.8%). Total tumor resection was achieved in 76.5%, visual improvement was recorded in 52.9%, and no complications were reported in 82.4% patients. Cerebrospinal fluid (CSF) leak was not reported in any of the studied patients. Finally, total resection was significantly associated with younger age, non-functioning tumor and improvement of headache.  The extended inferior turbinate flap is an effective and safe approach for sellar floor reconstruction in endoscopic endonasal surgery for recurrent pituitary tumors. The extension overcomes the relatively small inferior flap and its limited arc of rotation.

摘要

本研究的目的是探讨采用扩大下鼻甲瓣进行鞍底内镜重建的效果。

这是一项对34例复发性垂体瘤患者的回顾性研究。他们在2018年3月至2021年12月期间接受了内镜扩大经鼻入路手术,并用扩大的后蒂下鼻甲瓣重建鞍底。术后立即进行临床和影像学随访,并在术后1年内每3个月定期随访,将最后一次随访的可用数据纳入分析。

患者年龄在40至65岁之间,女性略占优势(55.9%)。头痛是主要表现(47.1%),50.0%的患者发现功能性肿瘤。61.8%的患者有视野缺损,52.9%的患者有视乳头水肿。术前内镜检查显示鼻中隔切除术后为主要发现(73.5%),其次是鼻中隔切除术后粘连(14.7%),最后是鼻中隔切除术后下鼻甲肥大(11.8%)。76.5%的患者实现了肿瘤全切,52.9%的患者视力改善,82.4%的患者未报告并发症。所有研究患者均未报告脑脊液漏。最后,全切与年龄较轻、无功能性肿瘤和头痛改善显著相关。

扩大下鼻甲瓣是复发性垂体瘤内镜经鼻手术中鞍底重建的一种有效且安全的方法。这种扩大克服了相对较小的下鼻甲瓣及其有限的旋转弧度。

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Extended inferior turbinate flap for endoscopic reconstruction of skull base defects.扩大下鼻甲瓣用于内镜下颅底缺损修复
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本文引用的文献

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Free Mucosal Graft for Reconstruction after Nonfunctional Pituitary Adenoma Surgery.游离黏膜移植用于无功能垂体腺瘤手术后的重建
Asian J Neurosurg. 2020 Oct 19;15(4):946-951. doi: 10.4103/ajns.AJNS_37_20. eCollection 2020 Oct-Dec.
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Advances in vascularized flaps for skull base reconstruction.颅底重建的血管化皮瓣进展。
Curr Opin Otolaryngol Head Neck Surg. 2021 Feb 1;29(1):36-43. doi: 10.1097/MOO.0000000000000690.
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Vascular pedicled flaps for skull base defect reconstruction.用于颅底缺损重建的血管蒂皮瓣
Laryngoscope Investig Otolaryngol. 2020 Oct 15;5(6):1029-1038. doi: 10.1002/lio2.471. eCollection 2020 Dec.

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