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典型胰腺错构瘤的影像学及组织病理学特征:1例报告并文献复习

Imaging and histopathologic characteristics of typical pancreatic hamartoma: a case report and literature review.

作者信息

Liu Shunli, Yang Lei, Wu Jie, Lin Xin, Zhang Zaixian

机构信息

Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Department of Radiology, Qingdao Women and Children's Hospital, Qingdao, China.

出版信息

Front Oncol. 2024 Aug 19;14:1418244. doi: 10.3389/fonc.2024.1418244. eCollection 2024.

DOI:10.3389/fonc.2024.1418244
PMID:39228982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11369897/
Abstract

BACKGROUND

Pancreatic hamartoma, a rare benign non-neoplastic condition, presents challenges in differentiating from other pancreatic diseases due to its atypical imaging and unreliable biopsy results. In this study, we present a case of pancreatic hamartoma and conduct a comprehensive review of relevant literature to outline its characteristic features, aiming to underscore its clinical relevance and implications.

CASE PRESENTATION

A 63-year-old man presented with a pancreatic mass, discovered during evaluation of abdominal pain and distension. Laboratory tests were largely unremarkable. Ultrasound revealed a hypoechoic mass in the head of the pancreas. Subsequent computed tomography and magnetic resonance imaging demonstrated an inhomogeneous mass with a clear boundary in the uncinate process of the pancreas. Furthermore, a distinct delayed enhancement pattern was noted on imaging. Histopathological examination confirmed the diagnosis of pancreatic hamartoma.

CONCLUSIONS

Preoperative diagnosis of pancreatic hamartoma remains challenging. Imaging modalities can play a crucial role in facilitating accurate diagnosis and potentially avoiding unnecessary surgical intervention in patients with this condition.

摘要

背景

胰腺错构瘤是一种罕见的良性非肿瘤性疾病,因其不典型的影像学表现和不可靠的活检结果,在与其他胰腺疾病的鉴别诊断中存在挑战。在本研究中,我们报告一例胰腺错构瘤病例,并对相关文献进行全面综述,以概述其特征,旨在强调其临床相关性和意义。

病例报告

一名63岁男性因腹痛和腹胀接受评估时发现胰腺肿块。实验室检查结果大多无异常。超声显示胰腺头部有一个低回声肿块。随后的计算机断层扫描和磁共振成像显示胰腺钩突部有一个边界清晰的不均匀肿块。此外,影像学检查发现了明显的延迟强化模式。组织病理学检查确诊为胰腺错构瘤。

结论

胰腺错构瘤的术前诊断仍然具有挑战性。影像学检查在促进准确诊断以及可能避免对患有这种疾病的患者进行不必要的手术干预方面可以发挥关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b8/11369897/6b92211d2fe3/fonc-14-1418244-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b8/11369897/d32f403c3768/fonc-14-1418244-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b8/11369897/6b92211d2fe3/fonc-14-1418244-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b8/11369897/d32f403c3768/fonc-14-1418244-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b8/11369897/6b92211d2fe3/fonc-14-1418244-g002.jpg

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本文引用的文献

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Pathologically confirmed pancreatic hamartoma after surgical resection with an aldosterone-producing adrenal tumor: a case report.手术切除醛固酮分泌性肾上腺肿瘤后经病理证实的胰腺错构瘤:一例报告
J Surg Case Rep. 2023 Aug 22;2023(8):rjad475. doi: 10.1093/jscr/rjad475. eCollection 2023 Aug.
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Pancreatic hamartoma: Possibility of a preoperative diagnosis via endoscopic ultrasound-guided fine-needle aspiration biopsy.胰腺错构瘤:经内镜超声引导下细针抽吸活检术术前诊断的可能性。
Diagn Cytopathol. 2023 Sep;51(9):E267-E272. doi: 10.1002/dc.25174. Epub 2023 May 31.
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Pancreatic hamartoma: A rare and benign cause of pancreatic incidentaloma.
胰腺错构瘤:胰腺偶发瘤的一种罕见良性病因。
Cir Esp (Engl Ed). 2022 Apr;100(4):250-254. doi: 10.1016/j.cireng.2022.03.010. Epub 2022 Apr 14.
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Rare case of pancreatic lipomatous hamartoma.胰腺脂肪瘤性错构瘤罕见病例。
BMJ Case Rep. 2022 Apr 7;15(4):e248132. doi: 10.1136/bcr-2021-248132.
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Fetal Pancreatic Hamartoma Associated with Hepatoblastoma-An Unusual Tumor Association.胎儿胰腺错构瘤合并肝母细胞瘤——一种罕见的肿瘤关联
Diagnostics (Basel). 2022 Mar 20;12(3):758. doi: 10.3390/diagnostics12030758.
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A case of solid-type pancreatic hamartoma presenting high apparent diffusion coefficient value: histopathological correlation and literature review.1例实性型胰腺错构瘤表现为高表观扩散系数值:组织病理学相关性及文献复习
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Pancreatic hamartoma mimicking neuroendocrine tumor.酷似神经内分泌肿瘤的胰腺错构瘤。
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