Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, Verona, Italy.
Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Pathologica. 2020 Sep;112(3):197-209. doi: 10.32074/1591-951X-168.
Inflammatory/tumor-like lesions of the pancreas represent a heterogeneous group of diseases that can variably involve the pancreatic gland determining different signs and symptoms. In the category of inflammatory/tumor-like lesions of the pancreas, the most important entities are represented by chronic pancreatitis, which includes alcoholic, obstructive and hereditary pancreatitis, paraduodenal (groove) pancreatitis, autoimmune pancreatitis, lymphoepithelial cyst, pancreatic hamartoma and intrapancreatic accessory spleen. An in-depth knowledge of such diseases is essential, since they can cause severe morbidity and may represent a potential life-threatening risk for patients. Furthermore, in some cases the differential diagnosis with malignant tumors may be challenging. Herein we provide a general overview of all these categories, with the specific aim of highlighting their most important clinic-pathological hallmarks to be used in routine diagnostic activities and clinical practice.
胰腺炎性/肿瘤样病变是一组异质性疾病，可不同程度累及胰腺，导致不同的症状和体征。在胰腺炎性/肿瘤样病变中，最重要的实体是慢性胰腺炎，包括酒精性、阻塞性和遗传性胰腺炎、十二指肠旁（沟）胰腺炎、自身免疫性胰腺炎、淋巴上皮囊肿、胰腺错构瘤和胰内副脾。深入了解这些疾病至关重要，因为它们可能导致严重的发病率，并可能对患者构成潜在的危及生命的风险。此外，在某些情况下，与恶性肿瘤的鉴别诊断可能具有挑战性。本文对所有这些类别进行了概述，旨在强调其在常规诊断活动和临床实践中最重要的临床病理特征。
