Wang Chaohui, Zhao Yuyang, Sun Zhenhua, Li Mingjun
Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Front Oncol. 2024 Aug 20;14:1422800. doi: 10.3389/fonc.2024.1422800. eCollection 2024.
GCA, also known as Buschke-Lowenstein tumor, is a rare sexually transmitted disease associated with HPV types 6 and 111. These warts are considered histologically benign, but there is a risk of localized invasion and development of malignancy. This malignant transformation occurs most often in the perianal and vulvar areas, and involvement of other sites is relatively rare2. In this case, we report a rare case of a giant wart originating from breast skin infected with HPV and progressing to cutaneous squamous cell carcinoma.
巨大尖锐湿疣,也称为Buschke-Lowenstein肿瘤,是一种与6型和11型人乳头瘤病毒相关的罕见性传播疾病。这些疣在组织学上被认为是良性的,但存在局部侵袭和恶变的风险。这种恶变最常发生在肛周和外阴区域,累及其他部位相对少见。在此病例中,我们报告了一例罕见的起源于感染人乳头瘤病毒的乳腺皮肤的巨大疣并进展为皮肤鳞状细胞癌的病例。