Buchanan C E
J Bacteriol. 1985 Jun;162(3):1302-3. doi: 10.1128/jb.162.3.1302-1303.1985.
Decoyinine, an inhibitor of GMP synthetase, was used to induce sporulation under catabolite-repressed conditions in Bacillus subtilis. Sporulation-specific penicillin-binding proteins 4* and 5* were produced in abundance, and there was an increase in vegetative penicillin-binding proteins 2B and 3. These results, which were completely blocked by addition of guanosine, suggest that synthesis of penicillin-binding proteins is neither catabolite repressed nor directly dependent on the stringent response.
脱氧精胍菌素，一种GMP合成酶抑制剂，被用于在枯草芽孢杆菌的分解代谢物阻遏条件下诱导芽孢形成。大量产生了芽孢形成特异性青霉素结合蛋白4和5，并且营养型青霉素结合蛋白2B和3有所增加。这些结果在添加鸟苷后被完全阻断，表明青霉素结合蛋白的合成既不受分解代谢物阻遏，也不直接依赖于严谨反应。
