Department of Medicine, University of Otago, Dunedin, New Zealand.
Department of Nephrology, Dunedin Public Hospital, Dunedin, New Zealand.
Nephrology (Carlton). 2024 Dec;29(12):960-963. doi: 10.1111/nep.14385. Epub 2024 Sep 4.
Herbaspirillum spp. is a common environmental bacterium usually found in soil, plant roots, and water. It is rarely associated with infection in immunocompromised patients, and rarely reported infections in immunocompetent patients. We report the first case of a Herbaspirillum huttiense bacteraemia in a non-neutropenic home haemodialysis patient. A 57-year-old male presented to our hospital with a 3-day history of malaise, fevers, rigours, and anorexia following dialysis through his central line. On examination, he was pyrexic (temperature 38.7°C) with splinter haemorrhages noted, but no other signs of infection were present. Blood cultures revealed a polymicrobial infection, with Serratia liquefaciens and Corynebacterium jeikeium isolated from the central line and Herbaspirillum sp. was isolated from both the central line and a peripheral culture. A later peripheral blood culture following central line removal isolated Herbaspirillum huttiense. Regular biological testing of his home water supply and dialysate detected no colony forming units of non-fermenting gram-negative bacilli. He was initially treated with ceftriaxone and vancomycin initially, followed by ertapenem and vancomycin. Intravenous antibiotics were ceased following 5 days after central line removal and he made an uneventful recovery.
希瓦氏菌属是一种常见的环境细菌,通常存在于土壤、植物根系和水中。它很少与免疫功能低下的患者的感染有关,在免疫功能正常的患者中也很少有感染的报道。我们报告了首例非中性粒细胞减少症的家庭血液透析患者感染希瓦氏菌属菌血症。一名 57 岁男性因透析中心静脉导管出现发热、寒战、厌食和不适 3 天而到我院就诊。体格检查发现患者发热(体温 38.7°C),有裂片样出血,但无其他感染迹象。血培养显示为混合微生物感染,中心静脉导管中分离出液化沙雷氏菌和杰氏棒状杆菌,外周培养物中分离出希瓦氏菌。在拔除中心静脉导管后进行的外周血培养分离出希瓦氏菌属 huttiense。对其家庭用水和透析液进行的常规生物学检测未发现非发酵革兰氏阴性杆菌的菌落形成单位。他最初接受头孢曲松和万古霉素治疗,随后改为厄他培南和万古霉素。在拔除中心静脉导管后 5 天,静脉内抗生素停止使用,他恢复良好,无并发症。