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一项关于在慢性肾脏病中实施药剂师处方的促进因素和障碍的定性、基于理论的探索。

A qualitative, theory-based exploration of facilitators and barriers for implementation of pharmacist prescribing in chronic kidney disease.

机构信息

Oman College of Health Sciences - Pharmacy programme, Muscat, Oman.

Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, Scotland.

出版信息

Int J Clin Pharm. 2024 Dec;46(6):1482-1491. doi: 10.1007/s11096-024-01794-y. Epub 2024 Sep 4.

Abstract

BACKGROUND

While there is an accumulation of evidence that pharmacist prescribing is safe and effective, there is a lack of research on processes of implementation into practice, particularly for patients with complex clinical conditions such as chronic kidney disease (CKD).

AIM

The aim was to explore the facilitators and barriers to the implementation of pharmacist prescribing for patients with CKD in the United Kingdom (UK).

METHOD

Semi-structured interviews were conducted with UK Renal Pharmacy Group members who were independent prescribers. The Consolidated Framework for Implementation Research (CFIR) underpinned the interview schedule. Interviews were recorded, transcribed, and independently coded by two researchers. A thematic approach was used for analysis, with data generation continuing until saturation of themes. Ethical approval was granted.

RESULTS

Data saturation was achieved following 14 interviews. Most interviewees were female (n = 11), all had secondary care as their main practice setting, and were highly experienced prescribers with 8 having 11 or more years of prescribing practice. Interviewees were positive regarding the development of their prescribing practice. Facilitators and barriers emerged across all 5 of the CFIR domains. Key facilitators were aspects of inner setting (e.g., organisational support and communication) while key barriers were also related to inner setting, specifically the need for adequate structural and financial resources.

CONCLUSION

This theory-based study has illuminated the facilitators and barriers for the implementation of pharmacist prescribing in CKD. There is a need to consider the resources required for implementation of prescribing practice at an early stage of planning and development.

摘要

背景

虽然有大量证据表明药剂师的处方是安全有效的,但对于将其付诸实践的实施过程的研究却很少,特别是对于患有慢性肾病(CKD)等复杂临床病症的患者。

目的

本研究旨在探索在英国(UK)实施药剂师为 CKD 患者开具处方的促进因素和障碍。

方法

对英国肾脏药房集团的独立处方持有者进行了半结构化访谈。访谈提纲以实施研究综合框架(CFIR)为基础。访谈由两名研究人员独立进行记录、转录和编码。采用主题方法进行分析,随着主题的不断发展,数据也在不断增加。本研究获得了伦理批准。

结果

在进行了 14 次访谈后达到了数据饱和。大多数受访者为女性(n=11),所有受访者的主要执业场所均为二级护理,并且是经验丰富的处方开具者,其中 8 人有 11 年或以上的处方开具经验。受访者对其处方开具实践的发展持积极态度。促进因素和障碍出现在 CFIR 的所有 5 个领域。主要的促进因素是内在环境的各个方面(例如,组织支持和沟通),而主要的障碍也与内在环境有关,特别是需要足够的结构和财务资源。

结论

这项基于理论的研究阐明了在 CKD 中实施药剂师处方的促进因素和障碍。在规划和发展的早期阶段,需要考虑实施处方实践所需的资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23e1/11576801/95a532454be2/11096_2024_1794_Fig1_HTML.jpg

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