Kirchner Thomas R, Tian Danning, Li Jian, Srivastava Pranjal, Zheng Yihao
Department of Social and Behavioral Sciences, School of Global Public Health, New York University, New York, NY 10003, United States.
Center for Urban Science and Progress, Tandon School of Engineering, New York University, New York, NY 10003, United States.
J Am Med Inform Assoc. 2024 Dec 1;31(12):2829-2836. doi: 10.1093/jamia/ocae237.
Research on the conditions under which electronic cigarette (EC) use produces a net reduction in the population harm attributable to combusted cigarette (CC) use requires the triangulation of information from cohort(s) of smokers, non-smokers, EC users, and dual-users of all varieties.
This project utilizes data from the All of Us Research Program to contrast a panel of wellness and disease-risk indicators across a range of self-reported tobacco-use profiles, including smokers, current, and former EC users. This article focuses on the tobacco use history and current tobacco use status among All of Us participants enrolled between May 2017 and February 2023 (Registered Controlled Tier Curated Data Repository [CDR] v7).
The present analytic sample included an unweighted total of N = 412 211 individuals with information on ever-use of both CC and EC. Among them, 155 901 individuals have a history of CC use, with 65 206 identified as current smokers. EC usage is reported by 64 002 individuals, with 16 619 being current users. Model predicted analyses identified distinct patterns in CC and EC usage across demographic and socioeconomic variables, with younger ages favoring ECs.
Age was observed to significantly affect EC usage, and gender differences reveal that males were significantly more likely to use CC and/or EC than females or African Americans of any gender. Higher educational achievement and income were associated with lower use of both CC and EC, while lower levels of mental health were observed to increase the likelihood of using CC and EC products.
Findings suggest the potential for the All of Us Research Program for investigation of causal factors driving both behavioral use transitions and cessation outcomes.
关于电子烟（EC）使用在何种条件下能使因燃烧香烟（CC）使用而导致的人群危害净减少的研究，需要对吸烟者、非吸烟者、电子烟使用者以及各类双重使用者群体的信息进行三角测量。
本项目利用“我们所有人”研究计划的数据，对比一系列自我报告的烟草使用情况（包括吸烟者、当前和以前的电子烟使用者）中的一组健康和疾病风险指标。本文重点关注2017年5月至2023年2月期间参与“我们所有人”研究的参与者的烟草使用历史和当前烟草使用状况（注册受控分层精选数据存储库[CDR]v7）。
当前分析样本包括总计N = 412211名未加权个体，他们有关于曾经使用过CC和EC的信息。其中，155901人有CC使用史，65206人被确定为当前吸烟者。64002人报告使用过EC，16619人是当前使用者。模型预测分析确定了CC和EC在人口统计学和社会经济变量方面的不同使用模式，年轻人更倾向于使用电子烟。
观察到年龄对电子烟使用有显著影响，性别差异表明男性比女性或任何性别的非裔美国人更有可能使用CC和/或EC。较高的教育成就和收入与CC和EC的较低使用相关，而心理健康水平较低会增加使用CC和EC产品的可能性。
研究结果表明，“我们所有人”研究计划有潜力用于调查驱动行为使用转变和戒烟结果的因果因素。
