移植和免疫功能低下患者中的 RSV。
RSV in transplant and immunocompromised patients.
机构信息
Section Head, Transplant Infectious Diseases, Department of Infectious Diseases, Cleveland Clinic, Cleveland, OH; Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
Center for Pediatric Infectious Diseases, Cleveland Clinic Children's Hospital, Cleveland, OH; Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
出版信息
Cleve Clin J Med. 2024 Sep 4;91(9 suppl 1):S34-S41. doi: 10.3949/ccjm.91.s1.06.
Respiratory syncytial virus (RSV) is a significant cause of morbidity and mortality in infants, older adults, and patients with weakened immune systems. Disease severity differs by underlying immunologic pathologies, with worse outcomes associated with progression from upper to lower respiratory disease. In this review we address the impact of RSV in immunocompromised populations, and discuss the limited available treatments and the potential impact of newer RSV prevention strategies on immunocompromised adults and children.
呼吸道合胞病毒（RSV）是导致婴儿、老年人和免疫系统较弱的患者发病和死亡的重要原因。疾病的严重程度因潜在的免疫病理学而异，从上呼吸道疾病进展为下呼吸道疾病与更差的预后相关。在这篇综述中，我们探讨了 RSV 在免疫功能低下人群中的影响，并讨论了有限的可用治疗方法以及新的 RSV 预防策略对免疫功能低下的成人和儿童的潜在影响。
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