Gerasimiak V G, Pruchanskiĭ V S, Litvinov P D, Vladimirova V A, Gnezdin B I
Med Radiol (Mosk). 1985 May;30(5):27-30.
The authors considered 3 variants of radiation therapy of esophageal cancer using megavoltage radiation sources: standard methods including a continuous course, optimized planning including a continuous and split irradiation course. In the use of megavoltage sources and a continuous irradiation course the 5-year survival was 8.8%. The use of a split course in rational dosimetric planning made it possible to improve the 3-year survival up to 22.4% in a split course and up to 11.2% in a continuous course. The use of the optimum dosimetric planning made it possible while irradiationg esophageal cancer patients to reduce radiation exposure of the pulmonary tissue and to achieve a decrease of severe forms of radiation pneumonia.
作者考虑了使用兆伏级辐射源治疗食管癌的3种放疗方案：包括连续疗程的标准方法、包括连续和分割照射疗程的优化计划。在使用兆伏级辐射源和连续照射疗程时，5年生存率为8.8%。在合理的剂量规划中采用分割疗程，在分割疗程中可将3年生存率提高到22.4%，在连续疗程中提高到11.2%。采用最佳剂量规划，在对食管癌患者进行照射时，可减少肺组织的辐射暴露，并降低严重放射性肺炎的发生率。
