Kudriavtseva G T, Iliukhin S A
Med Radiol (Mosk). 1985 May;30(5):37-43.
The authors presented 5-year results of combined therapy of malignant skin melanoma in 120 patients; of them 75 had primary skin melanoma, 45 recurrences in the scar, melanoma metastases to the skin, lymph nodes and soft tissues after inadequate treatment of primary melanoma. Preoperative intensive large fractionated radiotherapy with energy regulated fast electrons was used. In the group of patients with primary melanomas, the general 5-year survival was 73.3%, for Stage T1N0M0 93.8%, in the group of patients with secondary signs of melanoma 34.8%. This method of melanoma treatment made it possible to improve 5-year results, to reduce the time of treatment, to prevent the development of local recurrences; it did not cause radiation injuries.
作者报告了120例恶性皮肤黑色素瘤患者联合治疗的5年结果；其中75例为原发性皮肤黑色素瘤，45例为瘢痕复发、原发性黑色素瘤治疗不充分后发生的皮肤、淋巴结及软组织黑色素瘤转移。采用能量调节的快速电子进行术前强化大分割放疗。在原发性黑色素瘤患者组中，总体5年生存率为73.3%，T1N0M0期为93.8%，在有黑色素瘤继发征象的患者组中为34.8%。这种黑色素瘤治疗方法能够改善5年治疗结果，缩短治疗时间，预防局部复发；且未引起放射性损伤。
