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伴有“折叠人”畸形的强直性脊柱炎的手术治疗策略:一项单中心回顾性病例系列研究

Surgical Treatment Strategies for Ankylosing Spondylitis with "Folded Man" Deformity: A Single-Center Retrospective Case Series Study.

作者信息

Zhong Rui, Hu Zhengjun, Jiang Dengxu, Zhang Zhong, Wang Fei, Huang Huaqiang, Liang Yijian, Zhao Deng

机构信息

Department of Spine Surgery, The Third People's Hospital of Chengdu, Chengdu, China.

Department of Spine Surgery, The Third People's Hospital of Chengdu, Chengdu, China.

出版信息

World Neurosurg. 2024 Nov;191:e365-e372. doi: 10.1016/j.wneu.2024.08.132. Epub 2024 Sep 2.

DOI:10.1016/j.wneu.2024.08.132
PMID:39233311
Abstract

OBJECTIVE

Ankylosing spondylitis (AS) combined with severe kyphotic deformity can cause the trunk to collapse, pressing tightly against the front of the thighs and forming a "folded man" deformity. The purpose of this article is to evaluate the effectiveness and safety of a treatment strategy for correcting the "folded man" deformity.

METHODS

A retrospective study was conducted to analyze 12 AS patients with "folded man" deformity treated at our hospital with staged kyphosis correction in the lateral position, followed by total hip arthroplasty, from May 2018 to July 2021. Global kyphosis (GK), thoracic kyphosis, lumbar lordosis, sagittal vertical axis, chin-brow vertical angle, and Scoliosis Research Society-22 Patient Questionnaire scores were compared preoperation and postoperation. Surgical duration, positioning time, blood loss, and complications were also recorded and analyzed.

RESULTS

All patients demonstrated a correction of the "folded man" deformity, achieving sagittal balance and horizontal gaze with mild complications. Postoperatively, there were significant improvements in spinal sagittal parameters (GK, thoracic kyphosis, lumbar lordosis, and sagittal vertical axis) and chin-brow vertical angle compared to preoperative values (P < 0.05). The preoperative GK of 139.6 ± 9.1° was corrected to 55.3 ± 5.7° postoperatively, with a mean correction of 84.3°.

CONCLUSIONS

The standardized treatment strategy involving staged correction of spinal kyphosis in a lateral position, followed by subsequent total hip arthroplasty, offers a safe and effective solution for managing AS with "folded man" deformity.

摘要

目的

强直性脊柱炎(AS)合并严重驼背畸形可导致躯干塌陷,紧紧压迫大腿前部,形成“折叠人”畸形。本文旨在评估一种矫正“折叠人”畸形治疗策略的有效性和安全性。

方法

进行一项回顾性研究,分析2018年5月至2021年7月在我院接受分期侧位驼背矫正术,随后进行全髋关节置换术治疗的12例患有“折叠人”畸形的AS患者。比较术前和术后的全脊柱后凸(GK)、胸椎后凸、腰椎前凸、矢状垂直轴、眉-颌垂直角以及脊柱侧弯研究学会-22患者问卷评分。还记录并分析手术时长、摆位时间、失血量及并发症情况。

结果

所有患者的“折叠人”畸形均得到矫正,实现矢状面平衡和水平凝视,且并发症轻微。术后,与术前值相比,脊柱矢状面参数(GK、胸椎后凸、腰椎前凸和矢状垂直轴)及眉-颌垂直角有显著改善(P < 0.05)。术前GK为139.6±9.1°,术后矫正至55.3±5.7°,平均矫正84.3°。

结论

包括分期侧位脊柱后凸矫正术,随后进行全髋关节置换术的标准化治疗策略,为治疗伴有“折叠人”畸形的AS提供了一种安全有效的解决方案。

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