Elmoqaddem Hajar, Ayyad Anass, Messaoudi Sahar, Amrani Rim
Mother and Child Health Laboratory, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Department of Neonatology and Neonatal Resuscitation, Mohammed VI University Hospital, Oujda, MAR.
Cureus. 2024 Sep 4;16(9):e68663. doi: 10.7759/cureus.68663. eCollection 2024 Sep.
Congenital aplasia cutis (CAC) is a rare neonatal condition characterized by the absence of skin at birth, often associated with diverse underlying conditions. We report the case of a newborn male admitted on the second day of life with a skin defect on the anterior abdominal wall and a lesion on the left thigh. The mother was treated with carbimazole for hyperthyroidism. Notably, there were no similar cases in the family history. The patient showed favorable progress and normal development following a successful dermo-epidermal allograft. Particular attention was given to managing the risk of infection and ensuring optimal healing through tailored wound care protocols. This case underscores the complexity of CAC, highlighting the importance of early diagnosis, multidisciplinary care, and ongoing research to understand better and effectively treat this rare condition.
先天性皮肤发育不全（CAC）是一种罕见的新生儿疾病，其特征是出生时即无皮肤，常伴有多种潜在病症。我们报告了一例男婴病例，该男婴出生第二天入院，前腹壁有皮肤缺损，左大腿有一处病变。母亲因甲状腺功能亢进接受卡比马唑治疗。值得注意的是，家族史中无类似病例。在成功进行真皮-表皮同种异体移植后，患者病情进展良好，发育正常。通过定制的伤口护理方案，特别关注了感染风险的管理并确保最佳愈合。该病例强调了CAC的复杂性，突出了早期诊断、多学科护理以及持续研究对于更好地理解和有效治疗这种罕见疾病的重要性。
