逆行性环咽肌功能障碍（R-CPD）：我们目前了解多少？
Retrograde cricopharyngeal dysfunction (R-CPD): What do we know so far?
作者信息
Alotaibi Fahad Z
机构信息
Department of Otolaryngology-Head and Neck Surgery Imam Mohammad Ibn Saud Islamic University Riyadh Saudi Arabia.
出版信息
World J Otorhinolaryngol Head Neck Surg. 2023 Aug 6;10(3):231-236. doi: 10.1002/wjo2.127. eCollection 2024 Sep.
OBJECTIVE
This comprehensive review aims to explain the disease pathophysiology, clinical presentation, and management options.
METHODS
A review was carried out in the following databases: Medline, Scopus, Web of Science, and Cochrane. The following terms were used alone and combined: Retrograde, Cricopharyngeus muscle, Dysfunction, Abelchia, and inability to burp.
RESULTS
A total of 68 articles were identified, and only 11 were found to be relevant and included in writing this review. Retrograde cricopharyngeal dysfunction (R-CPD) is a relatively new disease entity that has recently been described in clinical literature. It is caused by the inability of the cricopharyngeus muscle to relax. Unlike cricopharyngeal dysfunction (CPD), which is well-known and characterized by dysphagia, R-CPD is characterized by the inability to belch in almost all patients, which is considered diagnostic for the condition.
CONCLUSIONS
High-resolution manometry (HRM) is the definitive diagnostic modality. Most patients reported in the literature responded well to treatment with botulinum toxin injection.
目的
本综述旨在解释该疾病的病理生理学、临床表现及治疗选择。
方法
在以下数据库进行检索：医学文献数据库（Medline）、Scopus数据库、科学引文索引（Web of Science）及考科蓝图书馆（Cochrane）。单独及组合使用以下检索词：逆行性、环咽肌、功能障碍、呃逆困难及不能嗳气。
结果
共识别出68篇文章，仅11篇被认为与本综述相关并纳入撰写。逆行性环咽肌功能障碍（R-CPD）是一种相对较新的疾病实体，近期在临床文献中有所描述。它由环咽肌无法松弛所致。与以吞咽困难为特征的环咽肌功能障碍（CPD）不同，R-CPD几乎在所有患者中均以不能嗳气为特征，这被视为该病的诊断依据。
结论
高分辨率测压法（HRM）是确诊的诊断方法。文献报道的大多数患者对肉毒杆菌毒素注射治疗反应良好。
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