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斜坡脊索瘤中的退行性异型性:两例报告

Degenerative Atypia in Clival Chordoma: Two Case Reports.

作者信息

Tena Suck Martha Lilia, Villanueva-Castro Eliezer, Munuzuri-Camacho Marco Antonio, Hernández Reséndiz Rebeca, Juárez-Cruz Samuel Ismael, Garcia-Diaz Oriana Carolina, Castro-Ibanez Jose Alfredo

机构信息

Department of Neuropathology, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, MEX.

Department of Neurosurgery, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, MEX.

出版信息

Cureus. 2024 Aug 5;16(8):e66197. doi: 10.7759/cureus.66197. eCollection 2024 Aug.

Abstract

In this study, we report surgical management combined with radiotherapy in two patients with typical chordoma. Different types of radiation have varied effects on chordomas when they are radiated. Classical cases display cellular atypia and fibrosis following irradiation, while necrosis and fibrosclerosis are observed after carbon ion therapy, implying that it is possible to control the tumor more effectively using carbon ion therapy with minimal side effects.

摘要

在本研究中,我们报告了两例典型脊索瘤患者的手术治疗联合放射治疗情况。不同类型的放射治疗在照射脊索瘤时会产生不同的效果。经典病例在照射后表现出细胞异型性和纤维化,而碳离子治疗后则观察到坏死和纤维硬化,这意味着使用碳离子治疗有可能以最小的副作用更有效地控制肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f04/11373669/0425f8c47bdf/cureus-0016-00000066197-i01.jpg

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