Kim Hayoon, Kang Sumin, Go Gwang-Woong
Department of Food and Nutrition, Hanyang University, Seoul, 04763 Republic of Korea.
Food Sci Biotechnol. 2024 Jul 10;33(13):2903-2917. doi: 10.1007/s10068-024-01656-3. eCollection 2024 Oct.
The ancient Ginkgo biloba tree grows across various regions, with distinctive leaves emitting a unique fragrance. Its extract contains flavonoids, organic acids, and terpenoids. Ginkgolide and bilobalide, which are leaf extracts, offer diverse pharmaceutical benefits, including antioxidant, anti-inflammatory, and neuroprotective properties. The antioxidant and anti-inflammatory properties of these compounds are crucial for mitigating neurodegeneration, particularly in diseases such as Alzheimer's disease. Additionally, their effectiveness in countering oxidative stress and inflammation highlights their potential to prevent cardiovascular ailments. This study also suggests that these compounds have a promising impact on lipid metabolism, suggesting their significance in addressing obesity-related metabolic disorders. In conclusion, ginkgolides and bilobalide exhibit promising effects in sustaining the integrity of the nervous and endocrine systems, along with the modulation of lipid metabolism. The diverse health benefits suggest that these compounds could serve as promising therapeutic interventions for various conditions, including neurological, cardiovascular, and metabolic diseases.
古老的银杏树生长在各个地区,其独特的叶子散发着独特的香气。它的提取物含有黄酮类化合物、有机酸和萜类化合物。银杏内酯和白果内酯作为叶子提取物,具有多种药用功效,包括抗氧化、抗炎和神经保护特性。这些化合物的抗氧化和抗炎特性对于减轻神经退行性变至关重要,尤其是在阿尔茨海默病等疾病中。此外,它们在对抗氧化应激和炎症方面的有效性凸显了其预防心血管疾病的潜力。这项研究还表明,这些化合物对脂质代谢有积极影响,表明它们在解决与肥胖相关的代谢紊乱方面具有重要意义。总之,银杏内酯和白果内酯在维持神经和内分泌系统的完整性以及调节脂质代谢方面显示出有前景的效果。多种健康益处表明,这些化合物可作为针对各种病症(包括神经、心血管和代谢疾病)的有前景的治疗干预措施。