Zhou Zhegang, Yu Longbiao, Meng Fanbin, Wen Jingjing, Xiao Yingfeng, Wan Shengxiang, Yan Jing, Zeng Hui, Yu Fei
Department of Hand & Microsurgery, Peking University Shenzhen Hospital, China.
Department of outpatient operating room, Peking University Shenzhen Hospital, China.
JPRAS Open. 2024 Jul 22;41:376-388. doi: 10.1016/j.jpra.2024.07.006. eCollection 2024 Sep.
As a chronic inflammatory process, chronic osteomyelitis is caused by bacterial infections that lead to bone destruction. This disease is more common in patients with open fractures and those undergoing multiple surgical procedures after trauma. We aimed to provide a comprehensive overview and critical assessment of the therapeutic efficacy of the anterolateral thigh (ALT) perforator flap in the management of chronic osteomyelitis with dermatologic and soft tissue imperfections localized in the lower extremity.
A retrospective analysis involving a cohort of 16 patients who underwent ALT perforator flap reconstruction for the management of chronic osteomyelitis in the calf region that manifested with integumentary deficiencies was conducted.
During the follow-up period spanning from 4 months to 2 years, all 16 patients who underwent ALT perforator flap transplantation exhibited flap viability. Among these cases, 15 patients made a full recovery from the infection and 1 patient had partial survival. Among the 15 cases, 2 patients developed vascular crisis (owing to venous thrombosis during surgical exploration). One patient had a relapse of the disease 1-year post-surgery. The success rate of this surgical method was 15/16, and the surgical complications included flap crisis, flap necrosis, delayed wound healing, and recurrence of infection.
The ALT perforator flap, which can cover bone and soft tissues and effectively control infections, can be applied to the treatment of chronic osteomyelitis of the lower limbs with skin defects. Overall, the muscle flap fills the dead space and medullary cavity and skin flap covers the skin defect.
慢性骨髓炎作为一种慢性炎症过程,由细菌感染导致骨破坏引起。这种疾病在开放性骨折患者以及创伤后接受多次外科手术的患者中更为常见。我们旨在全面概述并批判性评估股前外侧(ALT)穿支皮瓣在治疗伴有下肢皮肤和软组织缺损的慢性骨髓炎中的治疗效果。
对16例因小腿部慢性骨髓炎并伴有皮肤缺损而接受ALT穿支皮瓣重建手术的患者进行回顾性分析。
在4个月至2年的随访期内,所有16例行ALT穿支皮瓣移植的患者皮瓣均存活。其中,15例患者感染完全恢复,1例部分存活。15例中,2例发生血管危象(手术探查时因静脉血栓形成)。1例患者术后1年疾病复发。该手术方法的成功率为15/16,手术并发症包括皮瓣危象、皮瓣坏死、伤口愈合延迟和感染复发。
ALT穿支皮瓣可覆盖骨与软组织并有效控制感染,可应用于治疗伴有皮肤缺损的下肢慢性骨髓炎。总体而言,肌瓣填充死腔和髓腔,皮瓣覆盖皮肤缺损。