Jung Eujene, Kim Ho Goon, Kim Dong Ki, Ryu Hyun Ho
From the Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea (E.J., D.K.K., H.H.R.); Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea (E.J., H.H.R.); and Department of Gastroenterology, Chonnam National University Medical School, Gwangju, Korea (H.G.K.).
J Occup Environ Med. 2024 Dec 1;66(12):e630-e634. doi: 10.1097/JOM.0000000000003225. Epub 2024 Sep 4.
Our study aimed to investigate both the independent and combined effects of secondhand smoking (SHS) and alcohol intake on the occurrence of stroke.
Utilizing the Korean Genome Epidemiology Study prospective cohort data, our primary exposure variables were SHS exposure and alcohol intake. The occurrence of stroke served as the main outcome of interest. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression analysis. To assess the synergistic influence of SHS and alcohol intake on stroke incidence, a joint test was conducted.
SHS exposure correlated with an HR of 1.53 (95% CI = 1.19 to 1.98) for stroke risk. The combined exposure to SHS and alcohol yielded an elevated stroke risk, with an HR of 1.75 (95% CI = 1.20 to 2.55).
Our research highlights the combined influence of SHS exposure and alcohol intake on stroke susceptibility.
我们的研究旨在调查二手烟（SHS）和酒精摄入对中风发生的独立影响和联合影响。
利用韩国基因组流行病学研究前瞻性队列数据，我们的主要暴露变量是二手烟暴露和酒精摄入。中风的发生是主要关注的结果。使用Cox回归分析估计风险比（HRs）和95%置信区间（CIs）。为了评估二手烟和酒精摄入对中风发病率的协同影响，进行了联合检验。
二手烟暴露与中风风险的HR为1.53（95%CI = 1.19至1.98）相关。二手烟和酒精的联合暴露使中风风险升高，HR为1.75（95%CI = 1.20至2.55）。
我们的研究突出了二手烟暴露和酒精摄入对中风易感性的联合影响。
