González Díaz Irene, Méndez María Carmen, Tavecchia Mariana, Amor Costa Carmen, Amiama Roig Clara, Burgos García Aurora
Aparato Digestivo , Hospital Universitario La Paz, España.
Anatomía Patológica, Hospital Universitario La Paz.
Rev Esp Enferm Dig. 2025 Aug;117(8):466-467. doi: 10.17235/reed.2024.10633/2024.
Gastritis cystica profunda (GCP) is a rare entity characterized by foveolar hyperplasia and cystic dilation of the gastric mucosa and submucosal glands. Its etiopathogenesis remains unknown. It has been associated with chronic inflammatory conditions, such as gastric surgery or bile reflux. The diagnosis is histological, although endoscopic ultrasound (EUS) may be useful for initial suspicion. We present a series of cases from our center, where six cases of GCP were collected between 2012 and 2022, with no history of gastric surgery. The most common locations were the antrum (50%), fundus (33%), and body (17%). Endoscopic findings included polyps ranging from 7 to 50 mm. The treatment was en bloc mucosectomy for lesions ≤20 mm and piecemeal mucosectomy for lesions >20 mm. Recurrence was observed in four patients (67%). Histologically, displaced gastric glands were found in the submucosa with cystic dilation, without dysplastic changes.
胃深部囊肿性胃炎（GCP）是一种罕见的疾病，其特征为胃黏膜和黏膜下腺的小凹增生及囊性扩张。其发病机制尚不清楚。它与慢性炎症性疾病有关，如胃部手术或胆汁反流。诊断依靠组织学检查，尽管内镜超声（EUS）可能有助于初步怀疑。我们展示了我们中心的一系列病例，2012年至2022年间收集了6例GCP病例，均无胃部手术史。最常见的部位是胃窦（50%）、胃底（33%）和胃体（17%）。内镜检查结果包括大小为7至50毫米的息肉。对于直径≤20毫米的病变，治疗方法为整块黏膜切除术；对于直径>20毫米的病变，治疗方法为分块黏膜切除术。4例患者（67%）出现复发。组织学检查发现黏膜下层有移位的胃腺，伴有囊性扩张，无发育异常改变。
