Kersh C R, Eisert D R, Hazra T A
Radiology. 1985 Jul;156(1):207-9. doi: 10.1148/radiology.156.1.3923554.
Malignant thymoma is a rare tumor generally seen as an anterior mediastinal mass. Radiation therapy in ten patients with malignant thymoma diagnosed in 1968-1983 was reviewed retrospectively. Surgical therapy consisted of subtotal resection in four patients and biopsy only in six. Megavoltage irradiation in the dose range of 4,600-5,250 cGy was employed. In all symptomatic patients, palliation of presenting symptoms was achieved. In seven patients, a greater than 50% reduction in tumor mass followed radiation therapy. Local control was achieved in six patients. Three patients show no evidence of disease clinically, after a minimum follow-up study of 1 year. Radiation therapy is an important therapeutic modality in the control of malignant thymoma.
恶性胸腺瘤是一种罕见肿瘤，通常表现为前纵隔肿块。对1968年至1983年确诊的10例恶性胸腺瘤患者的放射治疗进行了回顾性研究。手术治疗包括4例患者的次全切除和6例患者的仅活检。采用了4600 - 5250 cGy剂量范围的兆伏级照射。在所有有症状的患者中，均实现了现有症状的缓解。7例患者放疗后肿瘤体积缩小超过50%。6例患者实现了局部控制。经过至少1年的随访研究，3例患者临床上无疾病证据。放射治疗是控制恶性胸腺瘤的重要治疗方式。
