Emory University, 1365B Clifton Road, NE Building B, Suite 4100, Office 4202, Atlanta, GA 30302, USA.
Emory University, 1365B Clifton Road, NE Building B, Suite 4100, Office 4202, Atlanta, GA 30302, USA.
Surg Clin North Am. 2024 Oct;104(5):1049-1064. doi: 10.1016/j.suc.2024.04.012. Epub 2024 May 23.
With improvements in surgical technique and advances in pancreatic endocrine and exocrine replacement therapy, the indications for, and threshold to perform, total or completion pancreatectomy in the modern surgical era are ever evolving. The following review will evaluate such indications for pancreatic cancer including pancreatic ductal adenocarcinoma and intraductal papillary mucinous neoplasms. The authors also review the literature on oncologic outcomes of total and completion pancreatectomy for pancreatic cancer. Finally, they discuss the quality of life and postoperative management of the a-pancreatic state.
随着手术技术的改进和胰腺内分泌和外分泌替代治疗的进步，在现代外科时代，进行全胰切除术或完成性胰切除术的适应证和阈值不断演变。以下综述将评估胰腺癌的这些适应证，包括胰腺导管腺癌和胰管内乳头状黏液性肿瘤。作者还回顾了全胰切除术和完成性胰切除术治疗胰腺癌的肿瘤学结果的文献。最后，他们讨论了无胰腺状态的生活质量和术后管理。
