Wiese M
Z Gesamte Inn Med. 1985 Mar 15;40(6):185-7.
Issuing from an analysis of the subjective and objective findings as well as of social data of 77 patients with histologically ascertained chronic persisting hepatitis after virus hepatitis non-A/non-B the problem is pursued whether or not - as in literature is nearly homogeneously assumed - the chronic persisting hepatitis is a decidedly benign disease. Apart from the difficulties in the clear histological classification mentioned by other authors it seemed to be profitable to demonstrate in detail the impairments by persisting symptoms which are to be established in the 5th year of the disease (75% of the patients), by acute attacks (ALAT max. 6.9 mymol/1 . s) with corresponding disabilities (40% of the patients) and the effects on social and professional life. The chronic persisting hepatitis is a very heterogeneous group, which must be considered more differentiated concerning the value of the disease and the prognosis. In this case the etiology must apparently more be taken into consideration, for the findings demonstrated in the 5th year of the disease of the chronic persisting hepatitis (non-A/non-B) show only partly (quoad vitam) a benign prognosis.
通过对77例经组织学确诊为非甲非乙型病毒性肝炎后慢性持续性肝炎患者的主观和客观检查结果以及社会数据进行分析,探讨了慢性持续性肝炎是否如文献中几乎一致认为的那样,是一种明显良性的疾病这一问题。除了其他作者提到的在明确组织学分类方面存在的困难外,详细展示疾病第5年(75%的患者)持续存在的症状所导致的损害、急性发作(谷丙转氨酶最高达6.9微摩尔/升·秒)及相应的功能障碍(40%的患者)以及对社会和职业生活的影响,似乎是有益的。慢性持续性肝炎是一个非常异质性的群体,在疾病的价值和预后方面必须更有区别地加以考虑。在这种情况下,显然必须更多地考虑病因,因为慢性持续性肝炎(非甲非乙型)在疾病第5年所显示的结果仅部分(就生活而言)显示出良性预后。