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手指 Spitz 样黑色素瘤:一例报告。

Spitzoid melanoma of the finger: a case report.

机构信息

Orthopedic Surgery and Traymatology, Habib Bourguiba Hospital, Sfax, Tunisia.

University of Medicine of Sfax, Sfax, Tunisia.

出版信息

J Med Case Rep. 2024 Sep 6;18(1):413. doi: 10.1186/s13256-024-04752-4.

Abstract

BACKGROUND

Melanoma is the most malignant skin tumor, with a high metastatic potential. Spitzoid melanoma is a subtype of melanoma requiring rapid management and extensive tumor resection. We have set the goal to recognize anatomical peculiarities and difficulties diagnoses posed by this type of tumor, as well as to recognize the management modalities, especially the surgical one, of malignant spitzoid melanoma.

CASE PRESENTATION

A 25-year-old Tunisian male patient had consulted for nodular lesion of the right index, evolving for 4 years. A malignant tumor was strongly suspected, then confirmed as a melanoma by a biopsy excision. Initially, the excision was incomplete in depth, suggesting a complementary surgery, but the patient refused it; 3 years later, the patient again consulted after the appearance of an axillary lymphadenopathy and worsening of the skin lesion. A supplement of tumor removal with lymph node biopsy were performed. It was decided to perform an amputation of the second ray and the first commissure with cheiroplasty, reconstructing a four-finger hand. An homolateral axillary cleaning was performed at the same time. The postoperative result is considered esthetically and functionally satisfying. The evolution was marked by the appearance of pulmonary metastases, requiring adjuvant chemotherapy. A regression of the nodule under the mammary skin and total disappearance of axillary nodes have been marked; but the patient's condition rapidly deteriorated, and he died after a 2-month decline.

CONCLUSION

Spitzoid melanoma is exceptional, posing difficulties in diagnostics, and it should not be underestimated, considering that it may involve the vital prognosis. Knowledge of this rare form of melanoma is important to avoid misdiagnosis, which delays diagnosis and subsequent therapy.

摘要

背景

黑色素瘤是最恶性的皮肤肿瘤,具有很高的转移潜能。Spitz 样黑色素瘤是一种需要快速处理和广泛肿瘤切除的黑色素瘤亚型。我们的目标是认识到这种类型肿瘤的解剖学特点和诊断困难,以及认识到恶性 Spitz 样黑色素瘤的治疗方式,特别是手术治疗方式。

病例介绍

一名 25 岁的突尼斯男性患者因右食指结节性病变就诊,该病变已存在 4 年。强烈怀疑为恶性肿瘤,活检切除后证实为黑色素瘤。最初,切除深度不完全,建议进行补充手术,但患者拒绝;3 年后,患者在出现腋窝淋巴结病和皮肤病变恶化后再次就诊。进行了肿瘤切除和淋巴结活检的补充手术。决定进行第二掌骨和第一掌骨间的截肢和手的成形术,重建四指手。同时进行同侧腋窝清扫术。术后结果在美学和功能上均令人满意。病情进展为出现肺部转移,需要辅助化疗。乳房皮肤下的结节和腋窝淋巴结完全消失,但患者病情迅速恶化,在 2 个月的下降后死亡。

结论

Spitz 样黑色素瘤罕见,诊断困难,不应低估,因为它可能涉及生命预后。了解这种罕见形式的黑色素瘤很重要,以避免误诊,延误诊断和随后的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e04/11378378/63e69ca7fb89/13256_2024_4752_Fig1_HTML.jpg

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