Koc Hakan, Uzunoğlu Seda
Faculty of Medicine, Department of Ophthalmology, Giresun University, Giresun, 28100, Turkey.
Int J Retina Vitreous. 2024 Sep 5;10(1):62. doi: 10.1186/s40942-024-00575-z.
To determine the potential relationship between age-related macular degeneration and iris freckles.
In this case-control study, iris photographs of 300 eyes of 300 patients diagnosed with age-related macular degeneration and 300 eyes of 300 healthy volunteers were obtained with the help of a high-resolution mobile phone camera. The evaluated iris photographs were classified according to the Descriptive Iris Color Classification Scale.
The average age of the AMD group is 73.05 ± 6.93, and the average age of the control group is 73.43 ± 5.72. (p = 0.124) While freckles were present in 200 (66.7%) of the patients in the AMD group, freckles were not observed in 100 patients (33.3%) of AMD group. While freckles were present in 142 (47.3%) of the patients in the control group, freckles were not observed in 158 of control group(52.7%). There was a significant difference in the presence of freckles between the two groups. (p < 0.001) The average number of freckles in the AMD group was 3.97 ± 3.07, and the number of freckles in the control group was 3.06 ± 2.55. (p = 0.001) CONCLUSION: We think that evaluation of iris details, especially the presence of iris freckles, should be used routinely in age-related macular degeneration screening. The risk of age-related macular degeneration can be predicted by evaluating iris details, which is an easy and inexpensive method.
确定年龄相关性黄斑变性与虹膜雀斑之间的潜在关系。
在这项病例对照研究中，借助高分辨率手机摄像头获取了300例被诊断为年龄相关性黄斑变性患者的300只眼睛以及300名健康志愿者的300只眼睛的虹膜照片。根据描述性虹膜颜色分类量表对评估的虹膜照片进行分类。
年龄相关性黄斑变性组的平均年龄为73.05±6.93，对照组的平均年龄为73.43±5.72。（p = 0.124）年龄相关性黄斑变性组中有200例患者（66.7%）存在雀斑，而年龄相关性黄斑变性组中有100例患者（33.3%）未观察到雀斑。对照组中有142例患者（47.3%）存在雀斑，而对照组中有158例患者（52.7%）未观察到雀斑。两组之间雀斑的存在情况存在显著差异。（p < 0.001）年龄相关性黄斑变性组的平均雀斑数量为3.97±3.07，对照组的雀斑数量为3.06±2.55。（p = 0.001）结论：我们认为，在年龄相关性黄斑变性筛查中应常规评估虹膜细节，尤其是虹膜雀斑的存在情况。通过评估虹膜细节可以预测年龄相关性黄斑变性的风险，这是一种简单且廉价的方法。
