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调查美国支气管和肺癌死亡率中的性别、种族及地域差异:一项利用美国疾病控制与预防中心(CDC)WONDER数据的全面纵向研究(1999 - 2020年)

Investigating sex, race, and geographic disparities in bronchus and lung cancer mortality in the United States: a comprehensive longitudinal study (1999-2020) utilizing CDC WONDER data.

作者信息

Alim Ur Rahman Hafsah, Ahmed Ali Fahim Muhammad, Salman Afia, Kumar Sateesh, Raja Adarsh, Raja Sandesh, Advani Damni, Devendar Raja, Khanal Anuva

机构信息

Dow Medical College, Dow University of Health Sciences.

Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.

出版信息

Ann Med Surg (Lond). 2024 Aug 7;86(9):5361-5369. doi: 10.1097/MS9.0000000000002387. eCollection 2024 Sep.

DOI:10.1097/MS9.0000000000002387
PMID:39238989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11374286/
Abstract

BACKGROUND

Lung and bronchus cancer has become the leading cause of cancer-related mortality in the United States. Understanding the patterns of mortality is an absolute requirement.

METHODS

This study analyzed Lung and Bronchus cancer-associated mortality rates from 1999 to 2020 using death certificate data from the Centers for Disease Control and Prevention Wide-Ranging OnLine Data for Epidemiologic Research (CDC WONDER). Age-adjusted mortality rates (AAMRs), per 100 000 people, and annual percentage change (APCs) were also calculated.

RESULTS

3 599 577 lung and bronchus cancer-related deaths occurred in patients aged younger than 1-85+ years between 1999 and 2020. Overall AAMRs declined from 59.1 in 1999 to 58.9 in 2001 (APC: -0.1364) then to 55.9 in 2005 (APC: -1.4388*) 50.5 by 2010 (APC: -2.0574*) 44.7 by 2014 (APC: -2.9497*) and 35.1 by 2020 (APC: -4.1040*). Men had higher AAMRs than women (overall AAMR men: 61.7 vs. women: 38.3). AAMRs were highest among non-Hispanic (NH) Black or African American (52.7) patients followed by NH White (51.8), NH American Indian or Alaska Native (38.6), NH Asian or Pacific Islander (24.7) and Hispanic or Latino race (20.2). AAMRs varied in region (overall AAMR; South: 52.4; Midwest: 52.3; Northeast: 46.3; West: 39.1). Non-metropolitan areas had a higher AAMR (55.9) as compared to metropolitan areas (46.7). The top 90 percentile states of Lung and Bronchus cancer AAMR were Arkansas, Kentucky, Mississippi, Tennessee, and West Virginia.

CONCLUSION

An overall decreasing trend in AAMRs for lung and bronchus cancer was seen. Public health measures to regulate risk factors and precipitating events are needed.

摘要

背景

肺癌已成为美国癌症相关死亡的主要原因。了解死亡率模式是绝对必要的。

方法

本研究使用美国疾病控制与预防中心的流行病学研究广泛在线数据(CDC WONDER)中的死亡证明数据,分析了1999年至2020年期间肺癌和支气管癌相关的死亡率。还计算了每10万人的年龄调整死亡率(AAMR)和年度百分比变化(APC)。

结果

1999年至2020年期间,年龄在1 - 85岁及以上的患者中有3599577例与肺癌和支气管癌相关的死亡。总体AAMR从1999年的59.1降至2001年的58.9(APC:-0.1364),然后降至2005年的55.9(APC:-1.4388*),2010年降至50.5(APC:-2.0574*),2014年降至44.7(APC:-2.9497*),2020年降至35.1(APC:-4.1040*)。男性的AAMR高于女性(男性总体AAMR:61.7,女性:38.3)。非西班牙裔(NH)黑人或非裔美国人患者的AAMR最高(52.7),其次是NH白人(51.8)、NH美洲印第安人或阿拉斯加原住民(38.6)、NH亚裔或太平洋岛民(24.7)以及西班牙裔或拉丁裔种族(20.2)。AAMR在不同地区有所不同(总体AAMR;南部:52.4;中西部:52.3;东北部:46.3;西部:39.1)。与大都市地区(46.7)相比,非大都市地区的AAMR更高(55.9)。肺癌和支气管癌AAMR处于前90百分位的州是阿肯色州、肯塔基州、密西西比州、田纳西州和西弗吉尼亚州。

结论

肺癌和支气管癌的AAMR总体呈下降趋势。需要采取公共卫生措施来管控风险因素和引发事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/d1840ca4c4af/ms9-86-5361-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/70c06e0812d3/ms9-86-5361-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/034a22d6ca5d/ms9-86-5361-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/7f788fb5eedb/ms9-86-5361-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/3adf7eb9ad53/ms9-86-5361-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/6936c429f1db/ms9-86-5361-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/d1840ca4c4af/ms9-86-5361-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/70c06e0812d3/ms9-86-5361-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/034a22d6ca5d/ms9-86-5361-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/7f788fb5eedb/ms9-86-5361-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/3adf7eb9ad53/ms9-86-5361-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/6936c429f1db/ms9-86-5361-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d45/11374286/d1840ca4c4af/ms9-86-5361-g006.jpg

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