Wali A, Safdar N, Ambreen A, Hassan S, Yaqoob A, Mustafa T
Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Department of Health, Government of Balochistan, Quetta, Pakistan.
Public Health Action. 2024 Sep 1;14(3):112-118. doi: 10.5588/pha.24.0012. eCollection 2024 Sep.
Quantifying quality of life (QoL) in extrapulmonary TB patients is crucial yet often overlooked. This study examines the impact of tuberculous lymphadenitis and pleuritis on patients' QoL, associated factors, and recurrence.
Data were collected prospectively from patients using a pre-designed questionnaire at baseline, post-treatment, and 2 years after treatment. Health domains are essential to overall health and well-being and can be assessed to understand health status. We included mobility for physical well-being, usual activities for self-care, pain/discomfort for disease manifestations, and anxiety/depression for emotional health.
Of the 376 patients, 53% had TB lymphadenitis, and 47% had TB pleuritis, with a mean age of 25 years (SD ±12.95). The most commonly reported issues at baseline were pain/discomfort and restricted usual activities. After treatment, over 90% experienced improvement, but 8% re-developed symptoms after 2 years, and two patients required retreatment for recurrent EPTB. Predictors negatively impacting QoL included private income sources, residence outside the city, and marriage, with the first two primarily affecting emotional health.
Tuberculous lymphadenitis and pleuritis significantly impact patients' physical and emotional health, necessitating healthcare providers to address non-medical factors affecting QoL to reduce morbidity and mortality and improve QoL.
量化肺外结核病患者的生活质量（QoL）至关重要，但往往被忽视。本研究探讨结核性淋巴结炎和胸膜炎对患者生活质量、相关因素及复发的影响。
前瞻性收集患者在基线、治疗后及治疗后2年使用预先设计问卷的数据。健康领域对整体健康和幸福至关重要，可通过评估来了解健康状况。我们纳入了身体状况方面的活动能力、自我护理方面的日常活动、疾病表现方面的疼痛/不适以及情绪健康方面的焦虑/抑郁。
376例患者中，53%患有结核性淋巴结炎，47%患有结核性胸膜炎，平均年龄25岁（标准差±12.95）。基线时最常报告的问题是疼痛/不适和日常活动受限。治疗后，超过90%的患者病情有所改善，但8%的患者在2年后再次出现症状，两名患者因复发性肺外结核病需要再次治疗。对生活质量有负面影响的预测因素包括私人收入来源、城外居住和婚姻状况，前两者主要影响情绪健康。
结核性淋巴结炎和胸膜炎显著影响患者的身心健康，医疗服务提供者必须解决影响生活质量的非医疗因素，以降低发病率和死亡率，提高生活质量。
