Xiao Zhen-Kun, Duan Yong-Hong, Mao Xin-Yu, Liang Ri-Chu, Zhou Min, Yang Yong-Mei
Hengyang Key Laboratory of Hemorrhagic Cerebrovascular Disease, Department of Neurosurgery, Hengyang Medical School, University of South China, Hengyang 421000, Hunan Province, China.
Department of Anatomy, Hengyang Medical School, University of South China, Hengyang 421000, Hunan Province, China.
World J Radiol. 2024 Aug 28;16(8):317-328. doi: 10.4329/wjr.v16.i8.317.
Minimally invasive surgery (MIS) and craniotomy (CI) are the current treatments for spontaneous supratentorial cerebral haemorrhage (SSTICH).
To compare the efficacy and safety of MIS and CI for the treatment of SSTICH.
Clinical and imaging data of 557 consecutive patients with SSTICH who underwent MIS or CI between January 2017 and December 2022 were retrospectively analysed. The patients were divided into two subgroups: The MIS group and CI group. Propensity score matching was performed to minimise case selection bias. The primary outcome was a dichotomous prognostic (favourable or unfavourable) outcome based on the modified Rankin Scale (mRS) score at 3 months; an mRS score of 0-2 was considered favourable.
In both conventional statistical and binary logistic regression analyses, the MIS group had a better outcome. The outcome of propensity score matching was unexpected (odds ratio: 0.582; 95%CI: 0.281-1.204; = 0.144), which indicated that, after excluding the interference of each confounder, different surgical modalities were more effective, and there was no significant difference in their prognosis.
Deciding between MIS and CI should be made based on the individual patient, considering the hematoma size, degree of midline shift, cerebral swelling, and preoperative Glasgow Coma Scale score.
微创手术(MIS)和开颅手术(CI)是目前治疗自发性幕上脑出血(SSTICH)的方法。
比较MIS和CI治疗SSTICH的疗效和安全性。
回顾性分析2017年1月至2022年12月期间连续接受MIS或CI治疗的557例SSTICH患者的临床和影像学资料。患者分为两个亚组:MIS组和CI组。进行倾向评分匹配以尽量减少病例选择偏倚。主要结局是基于3个月时改良Rankin量表(mRS)评分的二分法预后(良好或不良)结局;mRS评分为0-2被认为是良好的。
在传统统计分析和二元逻辑回归分析中,MIS组均有更好的结局。倾向评分匹配的结果出乎意料(优势比:0.582;95%CI:(0.281-1.204);P = 0.144),这表明在排除各混杂因素的干扰后,不同手术方式的疗效更佳,且其预后无显著差异。
在MIS和CI之间做出选择应根据患者个体情况,考虑血肿大小、中线移位程度、脑肿胀和术前格拉斯哥昏迷量表评分。