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苯酚关节神经松解术治疗慢性膝关节疼痛:病例系列

Genicular nerve neurolysis with phenol for chronic knee pain: A case series.

作者信息

Wilkinson Alex J, Chai Thomas, Roldan Carlos J, Huh Billy K

机构信息

-McGovern Medical School at UTHealth Houston, Houston, Texas, Harris County, USA.

-Department of Pain Medicine, Division of Anesthesiology, Critical Care Medicine, and Pain Medicine, M.D. Anderson Cancer Center, USA.

出版信息

Interv Pain Med. 2023 Feb 24;2(1):100182. doi: 10.1016/j.inpm.2023.100182. eCollection 2023 Mar.

Abstract

Chronic knee pain continues to be a common complaint amongst patients and continues to grow as the elderly population lives longer. New ways to treat chronic pain conditions, including chronic knee pain, are necessary as increased co-morbidities prevent patients from being surgical candidates. Recently, the genicular nerves have received more attention due to their role in innervating the anterior knee joint capsule as well as the intraarticular and extraarticular knee ligaments. Initial interest in the genicular nerve included radiofrequency ablation. RFA while effective, also brings with it increased procedure and equipment costs with a non-response rate of around 25%. Alcohol neurolysis of the genicular nerve is being seen as a potential alternative, low-cost, effective option for relieving chronic knee pain in patients. Previous case reports have focused on the use of alcohol, we report the use of phenol for genicular neurolysis. Of the four genicular nerve branches, only three are targeted due to the proximity of the inferolateral genicular nerve to the common peroneal nerve. The purpose of this case report is to show the effectiveness of phenol for neurolysis of the genicular nerves in relieving chronic knee pain in patients in which surgery is not an option.

摘要

慢性膝关节疼痛仍然是患者中常见的主诉,并且随着老年人口寿命的延长而持续增加。由于合并症增多使患者无法成为手术候选人,因此需要新的方法来治疗包括慢性膝关节疼痛在内的慢性疼痛病症。最近,膝神经因其在支配膝关节前关节囊以及关节内和关节外膝关节韧带中的作用而受到更多关注。对膝神经的最初兴趣包括射频消融。射频消融虽然有效,但也带来了手术和设备成本的增加,且无反应率约为25%。膝神经酒精神经溶解术被视为缓解患者慢性膝关节疼痛的一种潜在替代、低成本且有效的选择。以往的病例报告主要集中在酒精的使用上,我们报告了使用苯酚进行膝神经溶解术的情况。由于膝下外侧神经靠近腓总神经,在四条膝神经分支中,仅对其中三条进行靶向治疗。本病例报告的目的是展示苯酚用于膝神经溶解术在缓解不适合手术的患者慢性膝关节疼痛方面的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31cf/11372894/c550a1ced4b7/gr1.jpg

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