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制药企业如何利用实施科学放大产品价值。

How pharma can amplify product value with implementation science.

机构信息

Olson Strategies GmbH, Allschwil, 4123, Switzerland.

Center for Innovation to Accelerate Discovery & Practice Transformation (ADAPT), Durham Veterans Affairs Health Care & System, & Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC 27701, USA.

出版信息

J Comp Eff Res. 2024 Oct;13(10):e240076. doi: 10.57264/cer-2024-0076. Epub 2024 Sep 6.

Abstract

Achieving blockbuster status requires more than clinical trial success. Crucial barriers often include real-world factors like patient acceptance, prescriber behavior and timely and full reimbursement. Implementation science can be used to identify such barriers, develop strategies to overcome them, as well as test their effect. Used correctly and at the right time, implementation science can amplify product value and lead to a triple win for patients, healthcare systems and pharma. Three easy steps that focus on context, strategies and outcomes, can be followed by pharma to bring implementation thinking and research into their processes. A 'what if' case study is shared to give an indication of how this might work and the impact it might have.

摘要

要想取得重磅炸弹级药物的地位,仅仅临床试验成功是不够的。关键障碍通常包括现实世界中的一些因素,如患者接受度、医生行为以及及时和全额报销。实施科学可用于识别这些障碍,制定克服这些障碍的策略,并测试这些策略的效果。正确且适时地使用实施科学可以放大产品价值,为患者、医疗体系和制药企业带来三重获益。制药企业可以遵循三个注重背景、策略和结果的简单步骤,将实施思维和研究纳入其流程。通过一个“假设情景”案例研究,可以了解这可能如何运作以及可能产生的影响。

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