Department of Health Management Center, Third Xiangya Hospital, Central South University, Changsha 410011, China; Department of Psychiatry, the Second Xiangya Hospital of Central South University, National Center for Mental Disorders, National Clinical Research Center for Mental Disorders, Changsha 410011, China.
School of Education, Huazhong University of Science and Technology, Wuhan 430074, China.
Ecotoxicol Environ Saf. 2024 Oct 1;284:116967. doi: 10.1016/j.ecoenv.2024.116967. Epub 2024 Sep 5.
Mold exposure is a common environmental issue that can adversely affect health, particularly among older adults. The impact of mold exposure on anxiety symptoms in this population has not been extensively studied.
This study aims to examine the relationship between mold exposure and anxiety symptoms in older adults, considering the mediating role of cognitive function and the moderating effects of open window ventilation and multivitamin supplementation.
Data from the eighth wave of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) was utilized, including 11,021 participants aged 65 and older. Logistic regression models and moderated mediation analysis were employed to explore these relationships.
Mold exposure was significantly associated with increased anxiety symptoms (OR=1.831, 95 % CI=1.588-2.110). Cognitive impairment partially mediated this relationship. Open window ventilation (B=-0.040, P<0.001) and multivitamin supplementation (B=-0.197, P<0.001) served as protective factors. Subgroup analysis indicated higher vulnerability among females (OR=1.72, P<0.001), those aged 65-79 (OR=1.86, P<0.001), urban residents (OR=2.50, P<0.001), individuals not living with family members (OR=1.89, P<0.001), those with higher education (OR=2.01, P<0.001), married individuals (OR=1.80, P<0.001), and those in very good health (OR=2.11, P=0.026).
Mold exposure contributes to anxiety symptoms in older adults, with cognitive decline playing a mediating role. Effective interventions, including improved ventilation and multivitamin supplementation, can mitigate these effects. These findings highlight the need for targeted public health strategies to enhance the well-being of older adults.
霉菌暴露是一个常见的环境问题,可能对健康产生不利影响,尤其是在老年人中。霉菌暴露对这一人群焦虑症状的影响尚未得到广泛研究。
本研究旨在探讨老年人霉菌暴露与焦虑症状之间的关系,同时考虑认知功能的中介作用以及开窗通风和多种维生素补充的调节作用。
本研究使用了中国老年人纵向健康长寿调查(CLHLS)第八波的数据,共纳入了 11021 名 65 岁及以上的参与者。采用逻辑回归模型和调节中介分析方法来探讨这些关系。
霉菌暴露与焦虑症状的增加显著相关(OR=1.831,95%CI=1.588-2.110)。认知障碍部分介导了这种关系。开窗通风(B=-0.040,P<0.001)和多种维生素补充(B=-0.197,P<0.001)是保护因素。亚组分析表明,女性(OR=1.72,P<0.001)、65-79 岁(OR=1.86,P<0.001)、城市居民(OR=2.50,P<0.001)、与家人同住(OR=1.89,P<0.001)、受教育程度较高(OR=2.01,P<0.001)、已婚(OR=1.80,P<0.001)和健康状况良好(OR=2.11,P=0.026)的个体风险更高。
霉菌暴露会导致老年人出现焦虑症状,认知能力下降起到了中介作用。改善通风和多种维生素补充等有效干预措施可以减轻这些影响。这些发现强调了需要采取有针对性的公共卫生策略来提高老年人的幸福感。