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Enneking II + III 骨盆肿瘤切除术后不同固定类型的有限元分析。

Finite-element analysis of different fixation types after Enneking II + III pelvic tumor resection.

机构信息

Orthopaedic Hospital, The Second Hospital of Jilin University, Changchun, 130012, China.

Key Laboratory of Engineering Bionics, Ministry of Education, Jilin University, Changchun, 130012, China.

出版信息

Sci Rep. 2024 Sep 6;14(1):20878. doi: 10.1038/s41598-024-71334-1.

Abstract

The current primary treatment approach for malignant pelvic tumors involves hemipelvic prosthesis reconstruction following tumor resection. In cases of Enneking type II + III pelvic tumors, the prosthesis necessitates fixation to the remaining iliac bone. Prevailing methods for prosthesis fixation include the saddle prosthesis, ice cream prosthesis, modular hemipelvic prosthesis, and personalized prosthetics using three-dimensional printing. To prevent failure of hemipelvic arthroplasty protheses, a novel fixation method was designed and finite element analysis was conducted. In clinical cases, the third and fourth sacral screws broke, a phenomenon also observed in the results of finite element analysis. Based on the original surgical model, designs were created for auxiliary dorsal iliac, auxiliary iliac bottom, auxiliary sacral screw, and auxiliary pubic ramus fixation. A nonlinear quasi-static finite element analysis was then performed under the maximum load of the gait cycle, and the results indicated that assisted sacral dorsal fixation significantly reduces stress on the sacral screws and relative micromotion exceeding 28 μm. The fixation of the pubic ramus further increased the initial stability of the prosthesis and its interface osseointegration ability. Therefore, for hemipelvic prostheses, incorporating pubic ramus support and iliac back fixation is advisable, as it provides new options for the application of hemipelvic tumor prostheses.

摘要

目前,恶性骨盆肿瘤的主要治疗方法是在肿瘤切除后进行半骨盆假体重建。对于 Enneking Ⅱ+Ⅲ型骨盆肿瘤,假体需要固定在剩余的髂骨上。目前假体固定的方法有鞍式假体、冰淇淋假体、模块化半骨盆假体和使用三维打印的个性化假体。为了防止半骨盆关节置换假体失效,设计了一种新的固定方法并进行了有限元分析。在临床病例中,第三和第四骶骨螺钉断裂,这一现象也在有限元分析结果中观察到。基于原始手术模型,设计了辅助髂骨背侧、辅助髂骨底部、辅助骶骨螺钉和辅助耻骨支固定。然后在步态周期的最大负荷下进行非线性准静态有限元分析,结果表明辅助骶骨背侧固定可显著降低骶骨螺钉的应力和超过 28μm 的相对微动。耻骨支的固定进一步增加了假体的初始稳定性及其界面骨整合能力。因此,对于半骨盆假体,采用耻骨支支撑和髂骨背侧固定是可取的,这为半骨盆肿瘤假体的应用提供了新的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2556/11379819/397ca86f9132/41598_2024_71334_Fig1_HTML.jpg

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