Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts.
Wayne State University School of Medicine, Detroit, Michigan.
Pediatr Neurol. 2024 Dec;161:26-27. doi: 10.1016/j.pediatrneurol.2024.08.010. Epub 2024 Aug 22.
Vestibular paroxysmia is an episodic vestibular disorder resulting from compression or irritation of the eighth cranial nerve. This disorder is a rare and difficult diagnosis in children. We report the case of a 16-year-old adolescent male with a history of syncope and coronavirus disease 2019 infection four months prior who presented with intermittent episodes of vertigo and unsteadiness several times a week. These events started abruptly, and he appeared frozen. However, he remained conscious and was able to answer questions. He subsequently resumed normal activity in less than a minute without seizure stigmata or postictal period. His general and neurological examinations were unremarkable. Extensive diagnostic evaluation yielded negative results, except for an electrocardiogram consistent with Wolff-Parkinson-White syndrome. However, his symptoms persisted after cardiac ablation, suggesting they were not related to this arrhythmia. Following unsuccessful trials with various medications, his symptoms resolved with carbamazepine. Early recognition and appropriate treatment of this condition could substantially improve the quality of life for affected individuals.
前庭阵发性疾病是一种由第八颅神经受压或受刺激引起的阵发性前庭障碍。这种疾病在儿童中是一种罕见且难以诊断的疾病。我们报告了一例 16 岁青少年男性的病例,他有晕厥和新冠病毒感染的病史,在四个月前出现了间歇性眩晕和不稳,每周发作几次。这些事件突然发作,他看起来僵住了。然而,他保持清醒,并能够回答问题。随后,他在不到一分钟的时间内恢复了正常活动,没有癫痫发作的迹象或发作后状态。他的一般和神经系统检查无明显异常。广泛的诊断评估除了心电图符合 Wolff-Parkinson-White 综合征外,结果均为阴性。然而,在心脏消融术之后,他的症状仍然存在,表明与这种心律失常无关。在尝试了各种药物治疗均失败后,他的症状在使用卡马西平后得到了缓解。早期识别和适当治疗这种疾病可以显著提高患者的生活质量。