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唾液腺癌治疗进展。

Update on the Treatment of Salivary Gland Carcinomas.

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA.

Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA; Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9035, USA.

出版信息

Surg Oncol Clin N Am. 2024 Oct;33(4):747-760. doi: 10.1016/j.soc.2024.04.008. Epub 2024 Jul 16.

Abstract

Salivary gland carcinoma is a rare form of head and neck carcinoma, but it comprises a variety of subsites and histologic subtypes that each present with unique clinical courses and management challenges. Preoperative work-up generally consists of fine-needle aspiration cytology and MRI. However, because of the large variety of subtypes, there are often challenges obtaining a histologic diagnosis before surgery. Upfront surgery at the primary site leads to the greatest improvement in survival. Posttreatment surveillance of these patients is important. This article discusses some of the current controversies in the management of salivary gland carcinomas.

摘要

唾液腺癌是一种罕见的头颈部癌,但它包含多种亚部位和组织学亚型,每种亚型都具有独特的临床病程和管理挑战。术前检查通常包括细针抽吸细胞学检查和 MRI。然而,由于亚型种类繁多,在手术前通常很难获得组织学诊断。在原发部位进行早期手术可最大程度地提高生存率。对这些患者进行治疗后监测非常重要。本文讨论了唾液腺癌治疗中一些当前存在的争议。

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